322-97-4
322-97-4 structure
- Name: 7-(Trifluoromethyl)-4-quinolinol
- Chemical Name: 7-(trifluoromethyl)-1H-quinolin-4-one
- CAS Number: 322-97-4
- Molecular Formula: C10H6F3NO
- Molecular Weight: 213.156
- Catalog: Pharmaceutical intermediate Heterocyclic compound Quinoline compound
- Create Date: 2018-08-07 22:09:07
- Modify Date: 2024-01-13 17:52:25
| Name | 7-(trifluoromethyl)-1H-quinolin-4-one |
|---|---|
| Synonyms |
7-(trifluoromethyl)quinolin-4-ol
7-(Trifluoromethyl)-4-quinolinol 7-trifluoromethyl-quinolin-4-ol 4-Quinolinol, 7-(trifluoromethyl)- 7-trifluoromethyl-4-hydroxyquinoline 7-(trifluorophenyl)quinolin-4-ol EINECS 206-298-0 4-Hydroxy-7-(trifluoromethyl)quinoline 7-Trifluormethyl-chinolin-4-ol 7-TRIFLUOROMETHYL-4(1H)-QUINOLINONE MFCD00006779 7-(Trifluoromethyl)quinolin-4(1H)-one 4-Hydroxy-7-trifluoromethylquinoline 7-trifluoromethyl-4-quinolinol |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 311.9±37.0 °C at 760 mmHg |
| Melting Point | 266-269ºC(lit.) |
| Molecular Formula | C10H6F3NO |
| Molecular Weight | 213.156 |
| Flash Point | 142.4±26.5 °C |
| Exact Mass | 213.040146 |
| PSA | 33.12000 |
| LogP | 3.78 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.574 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26-37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933499090 |
|
~80%
322-97-4 |
| Literature: PFIZER INC. Patent: WO2005/63739 A1, 2005 ; Location in patent: Page/Page column 45-46 ; WO 2005/063739 A1 |
|
~%
322-97-4 |
| Literature: Journal of the American Chemical Society, , vol. 69, p. 371,373 |
|
~%
322-97-4 |
| Literature: Journal of Medicinal Chemistry, , vol. 41, # 25 p. 4918 - 4926 |
|
~%
322-97-4 |
| Literature: Journal of Medicinal Chemistry, , vol. 41, # 25 p. 4918 - 4926 |
| Precursor 4 | |
|---|---|
| DownStream 5 | |
![N,N-diethyl-N-[7-(trifluoromethyl)quinolin-4-yl]pentane-1,4-diamine structure](https://image.chemsrc.com/caspic/030/442-85-3.png)
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |