CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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NK8350000
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CHEMICAL NAME :
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Indene, 1-(4-dimethylaminobenzylidene)-
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CAS REGISTRY NUMBER :
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443-30-1
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LAST UPDATED :
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199712
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C18-H17-N
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MOLECULAR WEIGHT :
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247.36
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WISWESSER LINE NOTATION :
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L56 BYJ BU1R DN1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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2 gm/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,771,1970 ** TUMORIGENIC DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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270 mg/kg/15D-I
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Reproductive - Tumorigenic effects - ovarian tumors
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REFERENCE :
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NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 222,383,1969
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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4000 mg/kg/26W-C
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
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REFERENCE :
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PTEUA6 Pathologia Europaea. (Brussels, Belgium) V.1-11, 1966-76. Discontinued. Volume(issue)/page/year: 7,229,1972
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