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51989-25-4

51989-25-4 structure
51989-25-4 structure

Name L-Glutamic acid, N-[4-[[(2-amino-4-hydroxypyrido[3,2-d]pyrimidin-6-yl)methyl]amino]benzoyl]
Synonyms 8-deazafolic acid
Description 8-Deazafolic acid is an antimicrobial drug for the folate-dependent bacteria, Streptococcus faecium (ATCC 8043) and Lactobacillus casei (ATCC 74691). 8-Deazafolic acid has activity against lymphoid leukemia L1210 in mice[1].
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References

[1]. Carroll Temple Jr, et al. New synthesis of N-[4-[[(2-amino-4(3H)-oxopyrido[3,2-d]pyrimidin-6-yl)methyl]amino]benzoyl]-L-glutamic acid (8-deazafolic acid) and the preparation of some 5,6,7,8-tetrahydro derivatives. J. Med. Chem. 1981, 24, 10, 1254–1258.

Density 1.61g/cm3
Molecular Formula C20H20N6O6
Molecular Weight 440.40900
Exact Mass 440.14400
PSA 200.65000
LogP 2.01760
Index of Refraction 1.734