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78-90-0

78-90-0 structure
78-90-0 structure

Name propylenediamine
Synonyms 1,2-Diaminopropane
1,2-Propanediamine
EINECS 201-155-9
MFCD00008089
Density 0.87
Boiling Point 119-120ºC
Melting Point -37ºC
Molecular Formula C3H10N2
Molecular Weight 74.12490
Flash Point 33ºC
Exact Mass 74.08440
PSA 52.04000
LogP 0.69290
Vapour density 2.6 (vs air)
Vapour Pressure 14 mm Hg ( 20 °C)
Index of Refraction 1.445-1.447
Stability Stable. Flammable. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides.
Water Solubility SOLUBLE

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TX6650000
CHEMICAL NAME :
1,2-Propanediamine
CAS REGISTRY NUMBER :
78-90-0
BEILSTEIN REFERENCE NO. :
0605274
LAST UPDATED :
199709
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C3-H10-N2
MOLECULAR WEIGHT :
74.15
WISWESSER LINE NOTATION :
ZY1&1Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954
TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 3/12/1969
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,441,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 3/12/1969
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,441,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2230 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 3/12/1969
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
909 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ZEPTAT Zeitschrift fuer Experimentelle Pathologie und Therapie. (Berlin, Ger.) V.1-22, 1905-21. For publisher information, see REXMAS. Volume(issue)/page/year: 17,59,1915
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
593 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 97,1117,1977
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
500 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83465 No. of Facilities: 118 (estimated) No. of Industries: 7 No. of Occupations: 13 No. of Employees: 2614 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83465 No. of Facilities: 122 (estimated) No. of Industries: 3 No. of Occupations: 8 No. of Employees: 8346 (estimated) No. of Female Employees: 3070 (estimated)
Symbol GHS02 GHS05 GHS06 GHS08
GHS02, GHS05, GHS06, GHS08
Signal Word Danger
Hazard Statements H226-H302-H311-H314-H317-H334
Precautionary Statements P261-P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R10;R21/22;R35
Safety Phrases S26-S37/39-S45
RIDADR UN 2258
WGK Germany 1
RTECS TX6650000
Packaging Group II
Hazard Class 8
HS Code 29212900
HS Code 29212900