Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: L-Menthyl acetate
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Purity: 98.0%
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2623-23-6

2623-23-6 structure

Name: Menthyl acetate
Chemical Name: [(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] acetate
CAS Number: 2623-23-6
Molecular Formula: C₁₂H₂₂O₂
Molecular Weight: 198.302
Catalog: Flavors and spices Synthetic spice Carboxylic acid and ester perfume Aliphatic carboxylate
Create Date: 2018-05-11 08:00:00
Modify Date: 2026-07-19 07:12:28
Menthyl acetate (L-Menthyl acetate) is a derivative of L-menthol. Menthyl acetate is effective to enhance 5-aminolevulinic acid (ALA) skin permeation[1].

Name	[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] acetate
Synonyms	(-)-Acetic acid (1R,3R,4S)-p-menthan-3-yl ester L-MENTHYL ACETATE (1R)-(-)-MENTHYL ACETATE Acetic acid,L (-)-(1R)-MENTHYL ACETATE, TERPENE STANDA RD 2-isopropyl-5-methyl-,acetate,l-cyclohexan-1-o (1R,2S,5R)-2-isopropyl-5-Methylcyclohexyl acetate (5-Methyl-2-propan-2-ylcyclohexyl) acetate (IR)-(-)-MENTHYL ACETATE Cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1theta-(1alpha,2beta,5alpha)) l-p-menth-3-ylacetate (1R)-(-)-Menthyl acetate //BP (1R,2S,5R)-2-Isopropyl-5-methylcyclohexylacetat Cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1R-(1alpha,2beta,5alpha))- (9ci) menthyl (1R,2S,5R)-(-)-acetate L-(-)-2-isopropyl-5-methylcyclohexanol (-)-Menthyl Acetate acetate,(1r,3r,4s)-(-)-mentho (2S,1R,5R)-2-isopropyl-5-methylcyclohex-1-yl acetate l-(-)-Menthyl acetate (-)-Menthyl Acetate > EINECS 220-076-0 (1R)-(−)-Menthyl acetate (R)-(-)-MENTHYL ACETATE MENTHYL ACETATE, L MENTHYLACETAT NATUERLICH L-Menthylacetat Acetic acid, p-menth-3-yl ester, L laevo-menthyl acetate L-p-Menth-3-yl acetate (1R)-()-Menthyl acetate Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 1-acetate, (1R,2S,5R) cyclohexanol,5-methyl-2-(1-methylethyl)-,acetate,[1theta-(1alpha,2beta,5 (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl acetate (-)-ACETOXY-P-MENTHANE [(5R)-5-methyl-2-propan-2-ylcyclohexyl] acetate MENTHYL ACETATE, NATURAL (1R)-(-)-Menthyl acetate L -Menthyl acetate L-MENTHYL ACETATE NATURAL FCC (5R)-2-Isopropyl-5-methylcyclohexyl acetate Cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1R,2S,5R) aceticacid(1R)-menthylester cyclohexanol,5-methyl-2-(1-methylethyl)-,acetate,(1r-(1alpha,2beta,5alpha) L-Menthyl acetate (-)-(1R)-MENTHYL ACETATE Cyclohexan-1-ol, 2-isopropyl-5-methyl-, acetate, L (-)-Acetic acid (1R)-5β-methyl-2α-isopropylcyclohexan-1β-yl ester L-(-)-ACETOXY-P-MENTHANE Menthyl acetate, 10 mM in DMSO (-)-MENTHYL ACETATE WITH Menthyl acetate (-)-Menthol acetate 5-methyl-2-(1-methylethyl)-,acetate,[1R-(1.alpha.,2.beta.,5.alpha.)]-Cyclohexanol (-)-Acetoxy-p-menthane MENTHYL ACETATE, (-)-(SG) l-Menthol acetate (+)-Isocorynoline (1R,2S,5R)-rel-2-Isopropyl-5-methylcyclohexyl acetate L-Menthyl acetate,(1R)-Menthyl acetate MFCD00001482 Acetoxymenthane Cyclohexan-1-ol,acetate,L 1-MENTHYLACETATE (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl acetate Menthyl Acatate p-menth-3-ylester,l-aceticaci Brn

Description	Menthyl acetate (L-Menthyl acetate) is a derivative of L-menthol. Menthyl acetate is effective to enhance 5-aminolevulinic acid (ALA) skin permeation[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Tokuoka Y, et al. Enhancement in skin permeation of 5-aminolevulinic acid using l-menthol and its derivatives.Drug Dev Ind Pharm. 2008 Jun;34(6):595-601.

Density	0.9±0.1 g/cm3
Boiling Point	229.1±8.0 °C at 760 mmHg
Molecular Formula	C₁₂H₂₂O₂
Molecular Weight	198.302
Flash Point	92.2±0.0 °C
Exact Mass	198.161987
PSA	26.30000
LogP	4.10
Vapour Pressure	0.1±0.5 mmHg at 25°C
Index of Refraction	1.448

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AI5900000

CHEMICAL NAME :: Acetic acid, p-menth-3-yl ester, l-

CAS REGISTRY NUMBER :: 2623-23-6

BEILSTEIN REFERENCE NO. :: 2208505

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C12-H22-O2

MOLECULAR WEIGHT :: 198.34

WISWESSER LINE NOTATION :: L6TJ AY1&1 BOV1 D1 -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,477,1976 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,477,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,477,1976

Personal Protective Equipment	Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes	Xi
Safety Phrases	S24/25
RIDADR	NA 1993 / PGIII
WGK Germany	3
RTECS	AI5900000

Precursor 10
2216-51-5 64-19-7 108-05-4 108-24-7
75-36-5 15356-70-4 102-76-1 506-96-7
136375-73-0 108-22-5
DownStream 4
2216-51-5 64-19-7 2216-52-6 1753-40-8

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