587850-67-7
587850-67-7 structure
- Name: C7280948
- Chemical Name: 4-amino-N-(2-phenylethyl)benzenesulfonamide
- CAS Number: 587850-67-7
- Molecular Formula: C14H16N2O2S
- Molecular Weight: 276.354
- Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
- Create Date: 2018-12-07 10:42:23
- Modify Date: 2024-01-02 15:08:57
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C-7280948 is a PRMT1 inhibitor.IC50 value:Target: PRMT1in vitro: Especially arginine methyltransferases also target non-histone protein substrates and are therefore often called protein methyltransferases (PRMTs). The subtype PRMT1 has been linked to the activation of estrogen and androgen receptors and therefore may represent a new treatment option for hormone-dependent cancer. C-7280948 is a inhibitor, which is available for PRMT1.
| Name | 4-amino-N-(2-phenylethyl)benzenesulfonamide |
|---|---|
| Synonyms |
sulfanilic acid phenethylamide
Sulfanilsaeure-phenaethylamid 4-amino-N-phenethylbenzenesulfonamide 4-Amino-N-(2-phenylethyl)benzenesulfonamide Benzenesulfonamide, 4-amino-N-(2-phenylethyl)- C7280948 C-7280948 |
| Description | C-7280948 is a PRMT1 inhibitor.IC50 value:Target: PRMT1in vitro: Especially arginine methyltransferases also target non-histone protein substrates and are therefore often called protein methyltransferases (PRMTs). The subtype PRMT1 has been linked to the activation of estrogen and androgen receptors and therefore may represent a new treatment option for hormone-dependent cancer. C-7280948 is a inhibitor, which is available for PRMT1. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 481.1±55.0 °C at 760 mmHg |
| Molecular Formula | C14H16N2O2S |
| Molecular Weight | 276.354 |
| Flash Point | 244.8±31.5 °C |
| Exact Mass | 276.093262 |
| PSA | 80.57000 |
| LogP | 2.18 |
| Appearance | white solid |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.617 |
| Storage condition | -20℃ |
| HS Code | 2935009090 |
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|
~88%
587850-67-7 |
| Literature: Bissinger, Elisabeth-Maria; Heinke, Ralf; Spannhoff, Astrid; Eberlin, Adrien; Metzger, Eric; Cura, Vincent; Hassenboehler, Pierre; Cavarelli, Jean; Schuele, Roland; Bedford, Mark T.; Sippl, Wolfgang; Jung, Manfred Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 12 p. 3717 - 3731 |
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587850-67-7 |
| Literature: Journal of the Indian Chemical Society, , vol. 18, p. 316,319 |
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587850-67-7 |
| Literature: Bioorganic and Medicinal Chemistry, , vol. 19, # 12 p. 3717 - 3731 |
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~%
587850-67-7 |
| Literature: Journal of the Indian Chemical Society, , vol. 18, p. 316,319 |
| HS Code | 2935009090 |
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| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |