- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Fmoc-Lys-OH hydrochloride
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Sichuan Hengkang Science and Technology Development Co.,Ltd.
- China
- Product Name: Fmoc-Lys-OH-HCl
- Price: $Inquiry/1kg $Inquiry/1ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Teresa
- GL Biochem (Shanghai) Ltd.
- China
- Product Name: Fmoc-Lys-OH hydrochloride
- Price: ￥Inquiry/1kg ￥Inquiry/100g
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Jackie Yang
- Chengdu Pukang Biotechnology Co., Ltd.
- China
- Product Name: FMOC-LYS-OH HCL
- Price: ￥Inquiry/10kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Lihua Yang
- DC Chemicals Limited
- China
- Product Name: Fmoc-Lys-OH hydrochloride
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
139262-23-0
139262-23-0 structure
- Name: Fmoc-Lys-OH hydrochloride
- Chemical Name: (2S)-6-amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid,hydrochloride
- CAS Number: 139262-23-0
- Molecular Formula: C21H25ClN2O4
- Molecular Weight: 404.887
- Catalog: Biochemical Amino acids and their derivatives Lysine derivative
- Create Date: 2018-09-28 14:16:25
- Modify Date: 2024-01-02 18:25:49
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Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2].
| Name | (2S)-6-amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid,hydrochloride |
|---|---|
| Synonyms |
Nalpha-Fmoc-L-lysinehydrochloride
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-aminohexanoic acid hydrochloride Fmoc-Lys-OH hydrochloride Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-lysine Hydrochloride Fmoc-Lys-OH.HCl Fmoc-L-lysine HCl N2-Fmoc-L-lysine HCl MFCD00190889 Fmoc-L-lysine hydrochloride Nalpha-Fmoc-L-Lysine Hydrochloride L-Lysine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, hydrochloride (1:1) Nalpha-[(9H-Fluoren-9-ylMethoxy)carbonyl]-L-lysine Hydrochloride Fmoc-Lys-OH inverted exclamation mark currencyHCl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-lysine hydrochloride (1:1) Nα-Fmoc-L-lysine Hydrochloride |
| Description | Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Boiling Point | 607.6ºC at 760 mmHg |
|---|---|
| Molecular Formula | C21H25ClN2O4 |
| Molecular Weight | 404.887 |
| Flash Point | 321.3ºC |
| Exact Mass | 404.150299 |
| PSA | 101.65000 |
| LogP | 5.00050 |
| Vapour Pressure | 1.29E-15mmHg at 25°C |
| Index of Refraction | -11.0 ° (C=1, DMF) |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2924299090 |
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |