23130-22-5
23130-22-5 structure
- Name: Ladanetin
- Chemical Name: 5,6-dihydroxy-2-(4-hydroxyphenyl)-7-methoxychromen-4-one
- CAS Number: 23130-22-5
- Molecular Formula: C16H12O6
- Molecular Weight: 300.26300
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2016-06-11 12:42:13
- Modify Date: 2024-01-16 20:14:59
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Sorbifolin, a flavone glucoside, can be isolated from the Pterogyne nitens. Sorbifolin has myeloperoxidase inhibitory and radical scavenging activities. Sorbifolin is also a MPO inhibitor with an IC50 value of 19.2 nM[1].
| Name | 5,6-dihydroxy-2-(4-hydroxyphenyl)-7-methoxychromen-4-one |
|---|---|
| Synonyms |
7-O-methyl-seutellarin
5,6,4'-trihydroxy-7-methoxyflavone 7-methoxy-4',5,6-trihydroxyflavone 5,6-dihydroxy-7,4'-dimethoxyflavone 7-methylscutellarein Sorbifolin 7-O-methyl-seutellarein Ladanetin |
| Description | Sorbifolin, a flavone glucoside, can be isolated from the Pterogyne nitens. Sorbifolin has myeloperoxidase inhibitory and radical scavenging activities. Sorbifolin is also a MPO inhibitor with an IC50 value of 19.2 nM[1]. |
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| Related Catalog | |
| Target |
IC50: 19.2 nM (Myeloperoxidase, MPO)[1]. |
| In Vitro | Sorbifolin (30 min) 显示出自由基清除活性，清除 ABTS 自由基和 DPPH 自由基的 IC50 分别为 5.7 μM 和 13.5 μM[1]。 |
| References |
| Density | 1.512g/cm3 |
|---|---|
| Boiling Point | 601.7ºC at 760mmHg |
| Molecular Formula | C16H12O6 |
| Molecular Weight | 300.26300 |
| Flash Point | 230.2ºC |
| Exact Mass | 300.06300 |
| PSA | 100.13000 |
| LogP | 2.58540 |
| Vapour Pressure | 4.5E-15mmHg at 25°C |
| Index of Refraction | 1.697 |
| HS Code | 2914509090 |
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23130-22-5 |
| Literature: Krishnaswamy, N. R.; Rao, G. Nageswara; Omana, P. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 8 p. 750 - 752 |
| HS Code | 2914509090 |
|---|---|
| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |