52089-65-3

52089-65-3 structure

Name: (2H8)Hexanedioic acid
Chemical Name: adipic-db acid
CAS Number: 52089-65-3
Molecular Formula: C₆H₂D₈O₄
Molecular Weight: 154.191
Catalog: Research Areas Metabolic Disease
Create Date: 2018-03-26 08:00:00
Modify Date: 2024-01-12 20:41:47
Adipic acid-d8 is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

Name	adipic-db acid
Synonyms	Hexanedioic-d acid (H)Hexanedioic acid

Description	Adipic acid-d8 is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. G.Frauendienst-Egger, Friedrich K. Trefz (2017). MetaGene: Metabolic & Genetic Information Center. METAGENE consortium.

124-04-9

52089-65-3

25373-21-1

52089-65-3

Literature: Susi Spectrochimica Acta, 1959 , vol. 15, p. 1063,1067

Precursor 2
124-04-9 25373-21-1
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