52168-48-6

52168-48-6 structure

Name: Triacetonamine-d17
Chemical Name: 4-oxo-2,2,6,6-tetramethylpiperidine-d17
CAS Number: 52168-48-6
Molecular Formula: C₉D₁₇NO
Molecular Weight: 172.34200
Catalog: Research Areas Others
Create Date: 2018-04-18 08:00:00
Modify Date: 2024-01-05 21:18:43
Triacetonamine-d17 is the deuterium labeled Triacetonamine[1]. Triacetonamine is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine is an artifact of plant and fungal extracts using acetone and ammonium hydroxide or natural occurrence of ammonium salts in various steps of the isolation procedures. TAA is the main component of the pyrolysis oil[2].

Name	4-oxo-2,2,6,6-tetramethylpiperidine-d17

Description	Triacetonamine-d17 is the deuterium labeled Triacetonamine[1]. Triacetonamine is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine is an artifact of plant and fungal extracts using acetone and ammonium hydroxide or natural occurrence of ammonium salts in various steps of the isolation procedures. TAA is the main component of the pyrolysis oil[2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Cao JP, et al. Triacetonamine formation in a bio-oil from fast pyrolysis of sewage sludge using acetone as the absorption solvent. Bioresour Technol. 2010 Jun;101(11):4242-5.