5522-55-4

5522-55-4 structure

5522-55-4 structure

Name: Uracil-15N2
Chemical Name: 1H-1H-pyrimidine-2,4-dione-15N2
CAS Number: 5522-55-4
Molecular Formula: C₄H₄N₂O₂
Molecular Weight: 114.07400
Catalog: Research Areas Cancer
Create Date: 2018-05-12 08:00:00
Modify Date: 2024-01-11 19:49:58
Uracil-15N2 is the 15N labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].

Name	1H-1H-pyrimidine-2,4-dione-15N2
Synonyms	15N-labeled uracil Uracil-15N2 15N-enriched uracil MFCD00075013

Description	Uracil-15N2 is the 15N labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].
Related Catalog	Research Areas >> Cancer
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Pałasz A, et al. In search of uracil derivatives as bioactive agents. Uracils and fused uracils: Synthesis, biological activity and applications. Eur J Med Chem. 2015 Jun 5;97:582-611.

Density	1.321g/cm3
Melting Point	>300ºC (dec.)(lit.)
Molecular Formula	C₄H₄N₂O₂
Molecular Weight	114.07400
Exact Mass	114.02100
PSA	65.72000
Index of Refraction	1.501

RIDADR	NONH for all modes of transport

2067-80-3 structure

2067-80-3

471-25-0 structure

471-25-0

~73%

5522-55-4 structure

5522-55-4

Literature: LaFrancois, Christopher J.; Fujimoto, June; Sowers, Lawrence C. Chemical Research in Toxicology, 1998 , vol. 11, # 1 p. 75 - 83

Precursor 2
2067-80-3 471-25-0
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