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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: LYCORAMINE
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21133-52-8

21133-52-8 structure

21133-52-8 structure

Name: Lycoramine free base
Chemical Name: Lycoramine
CAS Number: 21133-52-8
Molecular Formula: C₁₇H₂₃NO₃
Molecular Weight: 289.36900
Catalog: API Nervous system medication Cholinergic
Create Date: 2018-07-30 16:34:16
Modify Date: 2026-07-06 09:10:11
Lycoramine, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor[1][2].

Name	Lycoramine
Synonyms	(-)-lycoramine (4aS,6S,8aS)-4a,5,7,8,9,10,11,12-Octahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef]benzazin-6-ol Galantamine hydrobromide Impurity C Galantamine Impurity 3（Galantamine Impurity C） Lycoramine,AChE,Inhibitor,radiate,dihydro-derivative,inhibit,galanthamine,acetylcholinesterase,Lycoris,Cholinesterase (ChE) (+-)-Lycoramin Galanthamine, 1,2-dihydro (4aS,8aS)-4a,5,7,8,9,10,11,12-Octahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef]benzazin-6β-ol LycoraMine HydrobroMide Galantamine Impurity C (Dihydro Galantamine) (4aS,8aS)-3-Methoxy-11-methyl-4aα,5,7,8,9,10,11,12-octahydro-6H-benzofuro[3a,3,2-ef]benzoazine-6β-ol Galantamine impurity C (4aS,6S,8aR)-4a,5,7,8,9,10,11,12-Octahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol Dihydrogalanthamine //BP Lycoramine, 10 mM in DMSO (4aS,6S,8) (4aS,6S,8-3-methoxy-11-methyl-5,6,7,8,9,10,11,12- octahydro-4aH-benzofuro[3a,3,2-ef]benzazin-6-ol Galantamine Impurity C (Dihydro Galantamine/ Lycoramine) (8aS)-3-Methoxy-5,6,7,8,9,10,11,12-octahydro-11-methyl-4aαH-benzofuro[3a,3,2-ef]benzazine-6β-ol Lycoramin 6H-Benzofuro[3a,3,2-ef]benzazin-6-ol, 4a,5,7,8,9,10,11,12-octahydro-3-methoxy-11-methyl-,(4aS,6S,8) Galanthamine, dihydro Galantamine hydrobromide Imp. C: (4aS,6S,8-3-methoxy-11-methyl-5,6,7,8,9,10,11,12-octahydro- 4aH-benzofuro[3a,3,2-ef]benzazin-6-ol (dihydrogalantamine) Galanthamine Impurity C Galantamine Hydrobromide Impurity Ⅰ:Galantamine Impurity C (Dihydro Galantamine)(4aS,6S,8-4a,5,7,8,9,10,11,12-Octahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef]benzazin-6-ol 1,2-Dihydrogalanthamine UNII-TAG8LU84K2 Dihydrogalanthamine

Description	Lycoramine, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	AChE[1]
References	[1]. Yuan Y, et, al. Online acetylcholinesterase inhibition evaluation by high-performance liquid chromatography-mass spectrometry hyphenated with an immobilized enzyme reactor. J Chromatogr A. 2020 Jan 4; 1609:460506. [2]. IRWIN RL, et, al. Cholinesterase inhibition by galanthamine and lycoramine. Biochem Pharmacol. 1960 May; 3:147-8.

Density	1.25
Boiling Point	436.4ºC at 760mmHg
Melting Point	122-124ºC
Molecular Formula	C₁₇H₂₃NO₃
Molecular Weight	289.36900
Flash Point	217.7ºC
Exact Mass	289.16800
PSA	41.93000
LogP	2.01220
Vapour Pressure	2.17E-08mmHg at 25°C
Index of Refraction	1.614
Storage condition	2-8°C

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