Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Butriptyline
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35941-65-2

35941-65-2 structure

35941-65-2 structure

Name: Butriptyline
Chemical Name: 3-(10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-N,N,2-trimethyl- 1-propanamine
CAS Number: 35941-65-2
Molecular Formula: C₂₁H₂₇N
Molecular Weight: 293.44600
Catalog: Research Areas Neurological Disease
Create Date: 2017-03-06 20:59:02
Modify Date: 2024-01-02 14:31:19
Butriptyline (Butriptylene) is an orally active tricyclic antidepressant agent[1].

Name	3-(10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-N,N,2-trimethyl- 1-propanamine
Synonyms	ButriptylineHCl Butriptylene hydrochloride butripyline 5-(2-Methyl-3-Dimethylaminopropyl)Dibenzo<a,d>Cycloheptadien Evadyne Butriptylin*HCl

Description	Butriptyline (Butriptylene) is an orally active tricyclic antidepressant agent[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vivo	Butriptyline (1000 mg/kg; in diet; 10 weeks) shows anti-obesity effect in mice[1]. Butriptyline hydrochloride (2.5-30 mg/kg; i.p.; 10-15 day intervals) causes a dose dependent depression of the food reinforced responses and slightly depresses the avoidance reflex at the highest doses in male albino rats[2]. Animal Model: Female CFLP mice, monosodium glutamate (MSG)-induced obesity model[1] Dosage: 1000 mg/kg Administration: In diet, 10 weeks Result: Significantly lowered the body weight.

Molecular Formula	C₂₁H₂₇N
Molecular Weight	293.44600
Exact Mass	293.21400
PSA	3.24000
LogP	4.50490

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HO8887000

CHEMICAL NAME :: 5H-Dibenzo(a,d)cycloheptene-5-propanamine, 10-11-dihydro-N,N,beta-trimethyl-, (+-)-

CAS REGISTRY NUMBER :: 35941-65-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H27-N

MOLECULAR WEIGHT :: 293.49

WISWESSER LINE NOTATION :: L C676&T&J B1Y1&1N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 75 mg/kg

SEX/DURATION :: female 4-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: JNMDBO Journal of Medicine (Westbury, NY). (PJD Pub., Ltd., POB 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 2,271,1971

RIDADR	UN 1851
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2921499090

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%