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  • BioBioPha
  • China
  • Product Name: Kukoamine A
  • Price: ¥Inquiry/5mg
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Xueping-Zheng

75288-96-9

75288-96-9 structure
75288-96-9 structure
  • Name: Kukoamine A
  • Chemical Name: N1,N12-bis(dihydrocaffeoyl)spermine
  • CAS Number: 75288-96-9
  • Molecular Formula: C28H42N4O6
  • Molecular Weight: 530.656
  • Catalog: Research Areas Cardiovascular Disease
  • Create Date: 2018-09-14 13:52:04
  • Modify Date: 2024-01-05 20:42:24
  • Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (Ki, 1.8 μM), with antihypertensive activity[1].

Name N1,N12-bis(dihydrocaffeoyl)spermine
Synonyms .N1,N14-bis(dihydrocaffeoyl)spermine
Kukoamine A
N,N'-[butane-1,4-diylbis(iminopropane-3,1-diyl)]bis[3-(3,4-dihydroxyphenyl)propanamide]
bis-dihydrocaffeoylspermine
N,N'-[1,4-Butanediylbis(imino-3,1-propanediyl)]bis[3-(3,4-dihydroxyphenyl)propanamide]
Benzenepropanamide, N,N'-[1,4-butanediylbis(imino-3,1-propanediyl)]bis[3,4-dihydroxy-
.kukoamine A
Description Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (Ki, 1.8 μM), with antihypertensive activity[1].
Related Catalog
Target

Ki: 1.8 μM (Trypanothione reductase)[1]

References

[1]. Ponasik JA, et al. Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase. Biochem J. 1995 Oct 15;311 ( Pt 2):371-5.

Density 1.2±0.1 g/cm3
Boiling Point 872.1±65.0 °C at 760 mmHg
Molecular Formula C28H42N4O6
Molecular Weight 530.656
Flash Point 481.2±34.3 °C
Exact Mass 530.310425
PSA 163.18000
LogP -0.17
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.588