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113-73-5

113-73-5 structure
113-73-5 structure
  • Name: Gramicidin S
  • Chemical Name: gramicidin S
  • CAS Number: 113-73-5
  • Molecular Formula: C60H92N12O10
  • Molecular Weight: 1141.447
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2018-03-18 08:00:00
  • Modify Date: 2025-08-25 18:26:22
  • Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic. Gramicidin S is active against Gram-negative and Gram-positive bacteria by perturbing integrity of the bacterial membranes. Gramicidin S also inhibits cytochrome bd quinol oxidase[1].

Name gramicidin S
Synonyms 5H,22H-dipyrrolo[1,2-a:1',2'-p][1,4,7,10,13,16,19,22,25,28]decaazacyclotriacontine-5,22-dione, 12,29-bis(3-aminopropyl)-1,2,3,6,9,12,15,17a,18,19,20,23,26,29,32,34a-hexadecahydro-8,11,14,17,25,28,31,34-octahydroxy-15,32-bis(1-methylethyl)-9,26-bis(2-methylpropyl)-6,23-bis(phenylmethyl)-, (6R,7E,9S,10E,12S,13E,15S,16E,17aS,23R,24E,26S,27E,29S,30E,32S,33E,34aS)-
Gramicidin C
Cyclo(L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl)
Gramacidine S [INN-French]
Gramicin S 1
Gramicidinum S [INN-Latin]
Gramicidina S [INN-Spanish]
gramicidin s
Gramicin S-A
Description Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic. Gramicidin S is active against Gram-negative and Gram-positive bacteria by perturbing integrity of the bacterial membranes. Gramicidin S also inhibits cytochrome bd quinol oxidase[1].
Related Catalog
References

[1]. Mogi T, et al. Gramicidin S and polymyxins: the revival of cationic cyclic peptide antibiotics. Cell Mol Life Sci. 2009 Dec;66(23):3821-6.  

Density 1.2±0.1 g/cm3
Boiling Point 1394.8±65.0 °C at 760 mmHg
Molecular Formula C60H92N12O10
Molecular Weight 1141.447
Flash Point 797.4±34.3 °C
Exact Mass 1140.705933
PSA 353.38000
LogP 0.10
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.596
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