83162-84-9

83162-84-9 structure

Name: Bonducellin
Chemical Name: Bonducellin
CAS Number: 83162-84-9
Molecular Formula: C₁₇H₁₄O₄
Molecular Weight: 282.29
Catalog: Research Areas Infection
Create Date: 2016-05-20 04:42:05
Modify Date: 2024-02-13 13:00:22
Bonducellin is a a homoisoflavonoid, which can be isolated from Caesalpinia digyna roots. Bonducellin is a potent inhibitor of efflux pump (EP), while EP induces resistance in mycobacteria and serves as a target of anti-TB (tuberculosis) agents. Bonducellin reduces MIC of EtBr by 8-fold against M. smegmatis (MIC=62.5 mg/L)[1].

Name	Bonducellin
Synonyms	(E)-7-hydroxy-3-(4'-methoxybenzylidene)chroman-4-one 7-hydroxy-(E)-3-[(4-methoxyphenyl)methylene]chroman-4-one bonducellin (E)-7-hydroxy-3-(4-methoxybenzylidene)chroman-4-one (3E)-2,3-dihydro-7-hydroxy-3-[(4-methoxyphenyl)-methylene]-4H-1-benzopyran-4-one bonducelline

Description	Bonducellin is a a homoisoflavonoid, which can be isolated from Caesalpinia digyna roots. Bonducellin is a potent inhibitor of efflux pump (EP), while EP induces resistance in mycobacteria and serves as a target of anti-TB (tuberculosis) agents. Bonducellin reduces MIC of EtBr by 8-fold against M. smegmatis (MIC=62.5 mg/L)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
References	[1]. Roy SK, et al. 7-Hydroxy-(E)-3-phenylmethylene-chroman-4-one analogues as efflux pump inhibitors against Mycobacterium smegmatis mc² 155. Eur J Med Chem. 2013 Aug;66:499-507.

Precursor 0
DownStream 1
610778-85-3