922163-64-2

922163-64-2 structure

Name: GlcNAcstatin
Chemical Name: Propanamide, 2-methyl-N-[(5R,6R,7R,8S)-5,6,7,8-tetrahydro-6,7-dihydroxy-5-(hydroxymethyl)-2-(2-phenylethyl)imidazo[1,2-a]pyridin-8-yl]
CAS Number: 922163-64-2
Molecular Formula: C₂₀H₂₇N₃O₄
Molecular Weight: 373.45
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2016-11-05 06:58:07
Modify Date: 2025-08-26 08:37:58
GlcNAcstatin is a selective glucoimidazole-based bacterial O-GlcNAcase inhibitor with a Ki of 4.6 pM. GlcNAcstatin shows 100000-fold selectivity over HexA/B[1].

Name	Propanamide, 2-methyl-N-[(5R,6R,7R,8S)-5,6,7,8-tetrahydro-6,7-dihydroxy-5-(hydroxymethyl)-2-(2-phenylethyl)imidazo[1,2-a]pyridin-8-yl]
Synonyms	GlcNAcstatin

Description	GlcNAcstatin is a selective glucoimidazole-based bacterial O-GlcNAcase inhibitor with a Ki of 4.6 pM. GlcNAcstatin shows 100000-fold selectivity over HexA/B[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Helge C Dorfmueller, et al. GlcNAcstatin: a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-glcNAcylation levels. J Am Chem Soc. 2006 Dec 27;128(51):16484-5.