852679-66-4

852679-66-4 structure

Name: (±)-LY 395756
Chemical Name: Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-4-methyl-, (1R,2R,4S,5S,6R)-rel
CAS Number: 852679-66-4
Molecular Formula: C₉H₁₃NO₄
Molecular Weight: 199.20
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2016-10-05 19:21:32
Modify Date: 2024-04-02 12:30:55
(±)-LY395756 is an agonist of mGlu2 receptor and an antagonist of mGlu3 receptor. (±)-LY395756 can distinguish the native mGlu2 and mGlu3 receptors[1].

Name	Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-4-methyl-, (1R,2R,4S,5S,6R)-rel
Synonyms	(±)-LY 395756 (+/-)-LY 395756 RS 17053 hydrochloride LY 395756

Description	(±)-LY395756 is an agonist of mGlu2 receptor and an antagonist of mGlu3 receptor. (±)-LY395756 can distinguish the native mGlu2 and mGlu3 receptors[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
References	[1]. Ceolin L, et al. Study of novel selective mGlu2 agonist in the temporo-ammonic input to CA1 neurons reveals reduced mGlu2 receptor expression in a Wistar substrain with an anxiety-like phenotype. J Neurosci. 2011 May 4;31(18):6721-31.