(±)-LY 395756

Modify Date: 2024-04-02 12:30:55

(±)-LY 395756 Structure
(±)-LY 395756 structure
Common Name (±)-LY 395756
CAS Number 852679-66-4 Molecular Weight 199.20
Density N/A Boiling Point N/A
Molecular Formula C9H13NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (±)-LY 395756


(±)-LY395756 is an agonist of mGlu2 receptor and an antagonist of mGlu3 receptor. (±)-LY395756 can distinguish the native mGlu2 and mGlu3 receptors[1].

 Names

Name Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-4-methyl-, (1R,2R,4S,5S,6R)-rel
Synonym More Synonyms

 (±)-LY 395756 Biological Activity

Description (±)-LY395756 is an agonist of mGlu2 receptor and an antagonist of mGlu3 receptor. (±)-LY395756 can distinguish the native mGlu2 and mGlu3 receptors[1].
Related Catalog
References

[1]. Ceolin L, et al. Study of novel selective mGlu2 agonist in the temporo-ammonic input to CA1 neurons reveals reduced mGlu2 receptor expression in a Wistar substrain with an anxiety-like phenotype. J Neurosci. 2011 May 4;31(18):6721-31.  

 Chemical & Physical Properties

Molecular Formula C9H13NO4
Molecular Weight 199.20
Exact Mass 199.08400
PSA 100.62000
LogP 0.45540

 Synonyms

(±)-LY 395756
(+/-)-LY 395756
RS 17053 hydrochloride
LY 395756