Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1-(2,3-Dihydro-1,4-benzodioxin-2-yl)methanamine
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,4-Benzodioxin-2-methanamine,2,3-dihydro-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

4442-59-5

4442-59-5 structure

4442-59-5 structure

Name: 1-(2,3-Dihydro-1,4-benzodioxin-2-yl)methanamine
Chemical Name: 2,3-dihydro-1,4-benzodioxin-3-ylmethanamine
CAS Number: 4442-59-5
Molecular Formula: C₉H₁₁NO₂
Molecular Weight: 165.189
Create Date: 2018-12-25 08:06:01
Modify Date: 2025-08-26 18:29:46

Name	2,3-dihydro-1,4-benzodioxin-3-ylmethanamine
Synonyms	1,4-BENZODIOXAN-2-METHYLAMINE C-(2,3-dihydrobenzo[1,4]dioxin-2-yl)methylamine 2-aminomethylbenzodioxane 1-(2,3-Dihydro-1,4-benzodioxin-2-yl)methanamine 1,4-Benzodioxin-2-methanamine, 2,3-dihydro- 2,3-Dihydro-1,4-benzodioxin-2-ylmethylamine Fourneau 946 2-aminomethyl-1,4-benzodioxan 1-(2,3-dihydro-1,4-benzodioxin-2-yl)methylamine (2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)amine 2,3-dihydro-1,4-benzodioxin-2-methanamine MFCD00203985 2-(3-CHLORO-4-FLUOROPHENOXY)ACETOHYDRAZIDE 2-aminomethyl-2,3-dihydro-1,4-benzodioxine LP 1 2-aminomethylbenzodioxan Aminomethylbenzodioxan EINECS 224-671-6 LP 1 (pharmaceutical)

Density	1.2±0.1 g/cm3
Boiling Point	266.0±19.0 °C at 760 mmHg
Melting Point	184-188°C
Molecular Formula	C₉H₁₁NO₂
Molecular Weight	165.189
Flash Point	124.1±28.8 °C
Exact Mass	165.078979
PSA	44.48000
LogP	0.92
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.545

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DF3676000

CHEMICAL NAME :: 1,4-Benzodioxan-2-methylamine

CAS REGISTRY NUMBER :: 4442-59-5

BEILSTEIN REFERENCE NO. :: 0150152

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H11-N-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 55,15,1937

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H315-H318-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi
Risk Phrases	R34
Safety Phrases	26-36/37/39
RIDADR	UN 2735
RTECS	DF3676000

1008-92-0 structure

1008-92-0

~84%

4442-59-5 structure

4442-59-5

Literature: Sanchez, Isabel; Dolors Pujol, Maria; Guillaumet, Gerald; Massingham, Roy; Monteil, Andre; Dureng, Georges; Winslow, Eileen European Journal of Medicinal Chemistry, 2000 , vol. 35, # 7-8 p. 663 - 676

3663-82-9 structure

3663-82-9

~87%

4442-59-5 structure

4442-59-5

Literature: Sun, Weilin; Pelletier, Jeffrey C. Tetrahedron Letters, 2007 , vol. 48, # 44 p. 7745 - 7746

128318-80-9 structure

128318-80-9

~%

4442-59-5 structure

4442-59-5

Literature: Xian, Ming; Li, Xiaopeng; Tang, Xiaoping; Chen, Xinchao; Zheng, Zhongling; Galligan, James J; Kreulen, David L; Wang, Peng G Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 17 p. 2377 - 2380

1094-91-3 structure

1094-91-3

~%

4442-59-5 structure

4442-59-5

Literature: Xian, Ming; Li, Xiaopeng; Tang, Xiaoping; Chen, Xinchao; Zheng, Zhongling; Galligan, James J; Kreulen, David L; Wang, Peng G Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 17 p. 2377 - 2380

2164-33-2 structure

2164-33-2

~%

4442-59-5 structure

4442-59-5

Literature: Marini-Bettolo et al. Gazzetta Chimica Italiana, 1953 , vol. 83, p. 144,147, 150

Precursor 5
1008-92-0 3663-82-9 128318-80-9 1094-91-3
2164-33-2
DownStream 10
46049-48-3 46049-49-4 2242-31-1 102071-90-9
101997-49-3 102071-89-6 102071-88-5 3562-90-1
2165-19-7 114461-88-0

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