352439-00-0

352439-00-0 structure

Name: Sodium 3-hydroxy(2,2-2H2)butanoate
Chemical Name: sodium 3-hydroxybutyrate-2,2-d2
CAS Number: 352439-00-0
Molecular Formula: C₄H₅D₂NaO₃
Molecular Weight: 128.099
Catalog: Research Areas Metabolic Disease
Create Date: 2018-07-23 17:59:05
Modify Date: 2024-01-06 20:09:45
3-Hydroxybutyric acid-d2 (sodium) is the deuterium labeled 3-Hydroxybutyric acid sodium[1]. 3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid sodium can modulate the properties of membrane lipids[2].

Name	sodium 3-hydroxybutyrate-2,2-d2
Synonyms	sodium dl-3-hydroxybutyrate-2,2-d2 Sodium 3-hydroxy(2,2-H)butanoate Butanoic-2,2-d acid, 3-hydroxy-, sodium salt (1:1)

Description	3-Hydroxybutyric acid-d2 (sodium) is the deuterium labeled 3-Hydroxybutyric acid sodium[1]. 3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid sodium can modulate the properties of membrane lipids[2].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Hsu TT, et al. 3-Hydroxybutyric acid interacts with lipid monolayers at concentrations that impair consciousness. Langmuir. 2013 Feb 12;29(6):1948-55.