90301-60-3

90301-60-3 structure

Name: 5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE
Chemical Name: 5-(2-hydroxyethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
CAS Number: 90301-60-3
Molecular Formula: C₁₁H₁₆N₂O₆
Molecular Weight: 272.25
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-12-20 17:23:15
Modify Date: 2024-01-12 11:52:20
5-(2-Hydroxyethyl)-2’-deoxy uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5-(2-hydroxyethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

Description	5-(2-Hydroxyethyl)-2’-deoxy uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

90301-69-2

90301-60-3

Literature: European Journal of Organic Chemistry, , # 10 p. 1989 - 1999

624-76-0

951-78-0

~49%

90301-60-3

Literature: Hassan, Mohamed E. Recueil des Travaux Chimiques des Pays-Bas, 1986 , vol. 105, # 1 p. 30 - 32

951-78-0

90301-60-3

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 105, # 1 p. 30 - 32

51432-34-9

90301-60-3

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 105, # 1 p. 30 - 32