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951-78-0

951-78-0 structure
951-78-0 structure
  • Name: 2'-deoxyuridine
  • Chemical Name: 2'-deoxyuridine
  • CAS Number: 951-78-0
  • Molecular Formula: C9H12N2O5
  • Molecular Weight: 228.202
  • Catalog: Biochemical Nucleoside drugs Nucleotides and their analogues
  • Create Date: 2018-07-13 18:09:14
  • Modify Date: 2024-01-02 16:25:49
  • 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine.
Name 2'-deoxyuridine
Synonyms Uracildeoxyr
deoxyuridine
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-hydroxy-2(1H)-pyrimidinone
T6NVMVJ A- ET5OTJ B1Q CQ &&Ribo-β-D Form
2'-deoxy-uridin
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-
1-(2-Deoxy-b-D-erythro-pentofuranosyl)uracil
[131I]-Deoxyuridine
2'-Deoxyuridine
Desoxyuridine
Uridine, 2'-deoxy-
MFCD00006527
2'-dU
EINECS 213-455-7
1-(2-Deoxy-D-erythro-pentofuranosyl)uracil
Deoxyribose uracil
1-(2-deoxy-β-D-ribofuranosyl)-2,4(1H,3H)-Pyrimidinedione
Deoxy-uridin
2′-Deoxyuridine
2(1H)-Pyrimidinone, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-4-hydroxy-
[3H]-Deoxyuridine
1-(2-deoxy-β-D-erythro-pentofuranosyl)uracil
1-(2-deoxy-β-δ-erythro-pentofuranosyl)-2,4(1H,3H)-Pyrimidinedione
1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
durd
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-ribofuranosyl)-
1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione
1-(2-deoxy-β-δ-ribofuranosyl)-2,4(1H,3H)-Pyrimidinedione
DEOXYURIDINE-2'
1-(2-deoxy-β-D-erythro-pentofuranosyl)-2,4(1H,3H)-Pyrimidinedione
1-(2-Deoxy-β-D-erythro-pentofuranosyl)pyrimidin-2,4(1H,3H)-dion
2'-DEOXYTHYMIDINE-5'-DIPHOSPHATE TRISODIUM SALT
1-(2-Deoxy-δ-erythro-pentofuranosyl)uracil
Description 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Reidy JA, et al. Deoxyuridine increases folate-sensitive fragile site expression in human lymphocytes. Am J Med Genet. 1987 Jan;26(1):1-5.
Density 1.5±0.1 g/cm3
Melting Point 167-169 °C(lit.)
Molecular Formula C9H12N2O5
Molecular Weight 228.202
Exact Mass 228.074615
PSA 104.55000
LogP -1.70
Index of Refraction 1.603
Storage condition 0-6°C
Water Solubility 300 g/L (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YU7490000
CHEMICAL NAME :
Uridine, 2'-deoxy-
CAS REGISTRY NUMBER :
951-78-0
BEILSTEIN REFERENCE NO. :
0024433
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C9-H12-N2-O5
MOLECULAR WEIGHT :
228.23

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
1 mmol/L
REFERENCE :
BICMBE Biochimie. (SPPIF, B.P.22, F-41353 Vineuil, France) V.53- 1971- Volume(issue)/page/year: 64,809,1982
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Risk Phrases R36/37/38
Safety Phrases S22-S24/25-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS YU7490000

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