Name | Sancycline |
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Synonyms |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)-
GS 2147 6-Demethyl-6-deoxytetracycline 6-demethyl-6-deoxy-tetracycline 6-deoxi-6-demethyl-tetracycline Bonomycin Sancycline (4S,4aS,5aR,12aS)-4-(Dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide Norcycline (4S,4aS,5aR,12aS)-4-(Dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide |
Description | Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin。Target:Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site. |
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Related Catalog |
Density | 1.6±0.1 g/cm3 |
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Boiling Point | 750.9±60.0 °C at 760 mmHg |
Melting Point | 224-228ºC (dec) |
Molecular Formula | C21H22N2O7 |
Molecular Weight | 414.409 |
Flash Point | 407.9±32.9 °C |
Exact Mass | 414.142700 |
PSA | 161.39000 |
LogP | -0.67 |
Vapour Pressure | 0.0±2.6 mmHg at 25°C |
Index of Refraction | 1.735 |
Storage condition | 2-8℃ |
Precursor 0 | |
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DownStream 1 | |