Sancycline

Modify Date: 2024-01-03 08:49:52

Sancycline Structure
Sancycline structure
Common Name Sancycline
CAS Number 808-26-4 Molecular Weight 414.409
Density 1.6±0.1 g/cm3 Boiling Point 750.9±60.0 °C at 760 mmHg
Molecular Formula C21H22N2O7 Melting Point 224-228ºC (dec)
MSDS N/A Flash Point 407.9±32.9 °C

 Use of Sancycline


Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin。Target:Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.

 Names

Name Sancycline
Synonym More Synonyms

 Sancycline Biological Activity

Description Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin。Target:Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.
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 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 750.9±60.0 °C at 760 mmHg
Melting Point 224-228ºC (dec)
Molecular Formula C21H22N2O7
Molecular Weight 414.409
Flash Point 407.9±32.9 °C
Exact Mass 414.142700
PSA 161.39000
LogP -0.67
Vapour Pressure 0.0±2.6 mmHg at 25°C
Index of Refraction 1.735
Storage condition 2-8℃

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)-
GS 2147
6-Demethyl-6-deoxytetracycline
6-demethyl-6-deoxy-tetracycline
6-deoxi-6-demethyl-tetracycline
Bonomycin
Sancycline
(4S,4aS,5aR,12aS)-4-(Dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide
Norcycline
(4S,4aS,5aR,12aS)-4-(Dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
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