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2540-82-1

2540-82-1 structure
2540-82-1 structure
  • Name: Formothion
  • Chemical Name: formothion
  • CAS Number: 2540-82-1
  • Molecular Formula: C6H12NO4PS2
  • Molecular Weight: 257.26800
  • Catalog: Biochemical Peptide
  • Create Date: 2018-03-29 08:00:00
  • Modify Date: 2025-08-24 12:52:00
  • Formothion is a chemical compound used in acaricides and insecticides.

Name formothion
Synonyms MFCD00210289
O,O-dimethyl S-(N-formyl-N-methylcarbamoyl-methyl)phosphorodithioate
Formothion 25 EC
S-[2-(Formylmethylamino)-2-oxoethyl] O,O-dimethyl dithiophosphate
Anthio
2-dimethoxyphosphinothioylthio-N-formyl-N-methylacetamide
EINECS 219-818-6
Antio
FORMOTHION
2-dimethoxyphosphinothioylsulfanyl-N-formyl-N-methylacetamide
S-[2-(N-methylformamido)-2-oxoethyl] O,O-dimethyl phosphorodithioate
Toprose
S-[2-(formylmethylamino)-2-oxoethyl]O,O-dimethyl phosphorodithioate
Aflix
Formothion solution
Anthio 25
Afliz [Sandoz]
S-[formyl(methyl)carbamoylmethyl] O,O-dimethyl phosphorodithioate
S-[2-(formylmethylamino)-2-oxoethyl] O,O-dimethyl phosphorodithioate
Density 1.368g/cm3
Boiling Point 317.8ºC at 760mmHg
Melting Point 25-26ºC
Molecular Formula C6H12NO4PS2
Molecular Weight 257.26800
Flash Point 25 °C
Exact Mass 256.99500
PSA 131.83000
LogP 1.59350
Vapour Pressure 0.000375mmHg at 25°C
Index of Refraction 1.544

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TE1050000
CHEMICAL NAME :
Phosphorodithioic acid, O,O-dimethyl ester, S-ester with N-formyl-2-mercapto-N-methyl- acetamide
CAS REGISTRY NUMBER :
2540-82-1
LAST UPDATED :
199703
DATA ITEMS CITED :
23
MOLECULAR FORMULA :
C6-H12-N-O4-P-S2
MOLECULAR WEIGHT :
257.28
WISWESSER LINE NOTATION :
VHN1&V1SPS&O1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4500 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
353 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
35 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
83300 ug/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - miosis (pupillary constriction) Cardiac - pulse rate Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
27 mg/m3
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - nausea or vomiting Liver - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
210 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
420 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - pigeon
DOSE/DURATION :
630 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
175 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - domestic
DOSE/DURATION :
630 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
471 mg/kg/43W-I
TOXIC EFFECTS :
Liver - fatty liver degeneration Endocrine - hyperglycemia Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
945 mg/kg/44W-I
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes Kidney, Ureter, Bladder - other changes in urine composition Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
489 mg/kg/30D-I
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Metabolism (Intermediary) - other proteins
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TEST SYSTEM :
Rodent - rat
DOSE/DURATION :
25 mg/kg
REFERENCE :
NULSAK Nucleus (Calcutta). (Dr. A.K. Sharma, Centre of Advanced Studies in Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta 700 019, India) V.1- 1958- Volume(issue)/page/year: 33,14,1990 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 46,1,1973 TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 63,1,1976 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.5 mg/m3;Skin JAN 1993
Symbol GHS02 GHS07 GHS08
GHS02, GHS07, GHS08
Signal Word Danger
Hazard Statements H226-H302 + H312 + H332-H304-H315-H319-H335-H373
Precautionary Statements P210-P260-P280-P301 + P310-P305 + P351 + P338-P370 + P378
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn
Risk Phrases R21/22
Safety Phrases S36/37-S36-S26
RIDADR 3018
Packaging Group III
Hazard Class 6.1(b)
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