41179-33-3
41179-33-3 structure
- Name: CMPD-1
- Chemical Name: 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide
- CAS Number: 41179-33-3
- Molecular Formula: C22H20FNO2
- Molecular Weight: 349.40
- Catalog: Signaling Pathways MAPK/ERK Pathway MAPKAPK2 (MK2)
- Create Date: 2016-02-01 22:32:04
- Modify Date: 2024-01-27 11:18:58
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CMPD1 is a selective and non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor with apparent Ki (Kiapp) of 330 nM[1][2].
| Name | 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide |
|---|---|
| Synonyms |
CMPD1
MK2a Inhibitor Mitogen-activated protein kinase-activated protein kinase 2a Inhibitor MAPKAPK2a Inhibitor |
| Description | CMPD1 is a selective and non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor with apparent Ki (Kiapp) of 330 nM[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Kiapp: 330 nM (MK2 phosphorylation)[2] |
| In Vitro | CMPD1 does not inhibit p38 MAPK-mediated phosphorylation of other two substrates, MBP and ATF2[1]. |
| References |
| Density | 1.229g/cm3 |
|---|---|
| Boiling Point | 585ºC at 760 mmHg |
| Molecular Formula | C22H20FNO2 |
| Molecular Weight | 349.40 |
| Flash Point | 307.6ºC |
| Exact Mass | 349.14800 |
| PSA | 49.33000 |
| LogP | 5.23270 |
| Index of Refraction | 1.627 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |