189744-46-5

189744-46-5 structure

Name: Ro 10-5824 dihydrochloride
Chemical Name: 5-(4-phenyl-3,6-dihydro-2H-pyridin-1-ylmethyl)-2-methyl-pyrimidin-4-ylamine
CAS Number: 189744-46-5
Molecular Formula: C₁₇H₂₂Cl₂N₄
Molecular Weight: 353.28900
Create Date: 2016-10-07 10:15:55
Modify Date: 2024-03-05 18:45:36
RO10-5824 is a D4-selective partial agonist. RO10-5824 is a potent candidate for the management of cocaine use disorders. The identification of effective medications for the management of cocaine use disorders remains an unmet public health challenge. In view of the prominent role of dopaminergic mechanisms in cocaine's abuse-related effects, research has focused on the development of subtype-selective dopamine D1-4 receptor antagonists.

Name	5-(4-phenyl-3,6-dihydro-2H-pyridin-1-ylmethyl)-2-methyl-pyrimidin-4-ylamine
Synonyms	Ro 10-5824 dihydrochloride RO 10-5824

43064-12-6

70476-08-3

189744-46-5

Literature: Hoffmann-La Roche Inc. Patent: US5688798 A1, 1997 ;

Precursor 2
43064-12-6 70476-08-3
DownStream 0