502486-89-7

502486-89-7 structure

Name: NIDA-41020
Chemical Name: 1-(2,4-dichlorophenyl)-5-(4-methoxyphenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide
CAS Number: 502486-89-7
Molecular Formula: C₂₃H₂₄Cl₂N₄O₂
Molecular Weight: 459.36800
Catalog: Signaling Pathways GPCR/G Protein Cannabinoid Receptor
Create Date: 2016-02-17 02:44:00
Modify Date: 2024-01-03 23:53:12
NIDA-41020 is a potent and selective cannabinoid receptor 1(CB1) antagonist with a Ki of 4.1 nM. NIDA-41020 was designed as a potential radioligand for use in positron emission tomography (PET)[1].

Name	1-(2,4-dichlorophenyl)-5-(4-methoxyphenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide
Synonyms	1-(2,4-Dichlorophenyl)-5-(4-methoxyphenyl)-4-methyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide Roxindole hydrochloride

Description	NIDA-41020 is a potent and selective cannabinoid receptor 1(CB1) antagonist with a Ki of 4.1 nM. NIDA-41020 was designed as a potential radioligand for use in positron emission tomography (PET)[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
Target	CB1:4.1 nM (Ki)
References	[1]. Katoch-Rouse R, et al. Synthesis, structure-activity relationship, and evaluation of SR141716 analogues: development of central cannabinoid receptor ligands with lower lipophilicity. J Med Chem. 2003 Feb 13;46(4):642-5.

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H300-H315-H319-H335
Precautionary Statements	P261-P264-P301 + P310-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Risk Phrases	25-36/37/38
Safety Phrases	26-45
RIDADR	UN 2811 6.1 / PGIII