CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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KG6125000
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CHEMICAL NAME :
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Estra-1,3,5,7,9-pentaen-17-one, 3-hydroxy-
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CAS REGISTRY NUMBER :
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517-09-9
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BEILSTEIN REFERENCE NO. :
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2335367
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LAST UPDATED :
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199709
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C18-H18-O2
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MOLECULAR WEIGHT :
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266.36
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WISWESSER LINE NOTATION :
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L E5 B666 FVTT&&J E1 OQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Implant
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SPECIES OBSERVED :
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Rodent - guinea pig
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DOSE/DURATION :
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1600 ug/kg
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - uterine tumors
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REFERENCE :
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BSBSAS Boletin de la Sociedad de Biologia de Santiago de Chile. (Santiago, Chile) V.1-12, 1943-55. Discontinued. Volume(issue)/page/year: 8,142,1951
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Implant
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SPECIES OBSERVED :
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Rodent - hamster
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DOSE/DURATION :
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640 mg/kg/38W-I
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors
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REFERENCE :
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CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,5200,1983
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Implant
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SPECIES OBSERVED :
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Rodent - guinea pig
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DOSE/DURATION :
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17 mg/kg
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - uterine tumors
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REFERENCE :
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RBBIAL Revista Brasileira de Biologia. Brazilian Review of Biology. (Academia Brasileira de Ciencias, Caixa Postal 229, ZC-00 Rio de Janeiro, Brazil) V.1- 1941- Volume(issue)/page/year: 5,1,1945
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