150849-52-8

150849-52-8 structure

Name: WST-1
Chemical Name: sodium,4-[2-(4-iodophenyl)-3-(4-nitrophenyl)tetrazol-2-ium-5-yl]benzene-1,3-disulfonate
CAS Number: 150849-52-8
Molecular Formula: C₁₉H₁₁IN₅NaO₈S₂
Molecular Weight: 651.34400
Catalog: Signaling Pathways Others Others
Create Date: 2018-06-21 18:31:26
Modify Date: 2024-01-31 23:00:15
WST-1 is a Tetrazolium dye, widely used in the cell viability assays. WST-1 produces a water-soluble formazan product (WST-1 formazan) that occurs at the cell surface in NADPH dependent manner in viable cells[1][2].

Name	sodium,4-[2-(4-iodophenyl)-3-(4-nitrophenyl)tetrazol-2-ium-5-yl]benzene-1,3-disulfonate
Synonyms	v1316 wst-1

Description	WST-1 is a Tetrazolium dye, widely used in the cell viability assays. WST-1 produces a water-soluble formazan product (WST-1 formazan) that occurs at the cell surface in NADPH dependent manner in viable cells[1][2].
Related Catalog	Signaling Pathways >> Others >> Others
In Vitro	WST-1 is used for a wide range of assays that include cell viability, proliferation, plasma membrane electron transport system, superoxide generation, superoxide dismutase, and xanthine oxidase assay[1]. A water-soluble formazan dye is produced from the reduction of WST-1 tetrazolium, of which optical density at 450 nm is measured to evaluate cell viability[1].
References	[1]. Kyung-Mi Joo, et al. Development and validation of UPLC method for WST-1 cell viability assay and its application to MCTT HCE™ eye irritation test for colorful substances. Toxicol In Vitro. 2019 Oct;60:412-419. [2]. Munetaka ISHIYAMA, et al. A new sulfonated tetrazolium salt that produces a highly water-soluble formazan dye. Chem. Pharm. Bull. 1993, 41(6): 1118-1122.

Hazard Codes	C