87304-15-2

87304-15-2 structure

Name: E3 ligase Ligand 9
Chemical Name: N-Boc bestatin
CAS Number: 87304-15-2
Molecular Formula: C₂₁H₃₂N₂O₆
Molecular Weight: 408.48900
Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
Create Date: 2016-07-14 08:09:46
Modify Date: 2024-01-10 13:27:05
E3 ligase Ligand 9 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 9 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

Name	N-Boc bestatin
Synonyms	(S)-2-[(2S,3R)-3-(tert-butoxycarbonylamino)-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid N-Boc-bestain N-Boc Bestatin

Description	E3 ligase Ligand 9 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 9 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> Ligand for E3 Ligase
References	[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

Hazard Codes	Xi

Precursor 0
DownStream 1
58970-76-6