DC Chemicals Limited
China
Product Name: (±)-Acetylcarnitine chloride
Price: ￥Inquiry/1g
Purity: 98.9%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Acetyl-DL-carnitine hydrochloride
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Contact: Ms Wang

2504-11-2

2504-11-2 structure

Name: acetyl-dl-carnitine hydrochloride
Chemical Name: (2-acetyloxy-3-carboxypropyl)-trimethylazanium,chloride
CAS Number: 2504-11-2
Molecular Formula: C₉H₁₈ClNO₄
Molecular Weight: 239.69700
Catalog: Research Areas Neurological Disease
Create Date: 2018-05-13 08:00:00
Modify Date: 2024-01-05 14:03:11
(±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with cholinergic properties. (±)-Acetylcarnitine chloride is an important intermediate in lipid metabolism[1][2].

Name	(2-acetyloxy-3-carboxypropyl)-trimethylazanium,chloride
Synonyms	rac. Acetylcarnitinchlorid Acetylcarnitin-chlorid rac. Acetyl-carnithin EINECS 219-709-3 O-Acetylcarnitinhydrochlorid Acetyl dl-carnitine chloride MFCD00080826 Evans Blue tetrasodium salt Acetyl-DL-carnitine hydrochloride

Description	(±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with cholinergic properties. (±)-Acetylcarnitine chloride is an important intermediate in lipid metabolism[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vitro	Large increases of Acetylcarnitine concentration during the flight of the blowfly and the presence of an active Acetylcarnitine transferase indicate that Acetylcarnitine is important in carbohydrate metabolism. Acetylcarnitine has been synthesized by the choline acetylase system isolated from brain tissue and is destroyed by cholinesterase[2].
In Vivo	In rats, the infusion of 2 mg (±)-Acetylcarnitine chloride decreases blood flow through the hind limb vasculature 50%. (±)-Acetylcarnitine chloride also potentiates the inhibitory effect of adrenaline on the isolated rabbit duodenum[3].
References	[1]. R A Chalmers, et al. Urinary excretion of l-carnitine and acylcarnitines by patients with disorders of organic acid metabolism: evidence for secondary insufficiency of l-carnitine. Pediatr Res. 1984 Dec;18(12):1325-8. [2]. R L Sass, et al. Acetylcarnitine: on the relationship between structure and function. Biochem Biophys Res Commun. 1973 Dec 10;55(3):736-42. [3]. R T Louis-Ferdinand, et al. Flow decrease through rat hind limb vasculature by (plus or minus)-carnitine, (plus or minus)-acetylcarnitine and (plus or minss)-chloroacetylcarnitine chlorides. J Pharm Pharmacol. 1970 Sep;22(9):704-5.

Molecular Formula	C₉H₁₈ClNO₄
Molecular Weight	239.69700
Exact Mass	239.09200
PSA	63.60000
Storage condition	−20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BP2979200

CHEMICAL NAME :: Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, chloride, acetate, (+-)-

CAS REGISTRY NUMBER :: 2504-11-2

LAST UPDATED :: 198912

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H17-N-O4.Cl

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7400 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - fluid intake Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 3,28,1959

RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	BP2979200

Precursor 0
DownStream 1
546-88-3

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