555-29-3

555-29-3 structure
555-29-3 structure
  • Name: 3-Hydroxy-alpha-methyl-DL-tyrosine
  • Chemical Name: 2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid
  • CAS Number: 555-29-3
  • Molecular Formula: C10H13NO4
  • Molecular Weight: 211.214
  • Create Date: 2018-07-29 15:07:18
  • Modify Date: 2024-01-12 07:59:40

Name 2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid
Synonyms a-Methyl-L-dopa
α-Methyl-L-dopa
Dopegyt
EINECS 209-088-7
3-(3,4-Dihydroxyphenyl)-2-methyl alanine
L-(-)-b-(3,4-Dihydroxyphenyl)-a-methylalanine
L-(-)-α-Methyl-β-(3,4-dihydroxyphenyl)alanine
L-(-)-a-Methyl-b-(3,4-dihydroxyphenyl)alanine
rac Alpha-Methyl DOPA
2-Methyl-3-(3,4-dihydroxyphenyl)-DL-alanine
a-Methyl Dopa
(+)-α-Methyldopa
Mulfasin
UNII:33TD13T99R
α-Methyl dopa
3-Hydroxy-α-methyltyrosine
Metholes
Tyrosine, 3-hydroxy-α-methyl-
L-(a-Md)
L-α-Methyldopa
(-)-α-Methyldopa
3-Hydroxy-α-methyl-L-tyrosine
L-Tyrosine, 3-hydroxy-α-methyl-
Dopamet
(S)-(-)-a-Methyldopa
a-Methyl-b-(3,4-dihydroxyphenyl)-L-alanine
Bayer 1440L
MFCD00065917
Methyl dopa
Aldomet
l-a-Methyldopa
(S)-a-Methyldopa
ALDORIL
Alanine, 3- (3,4-dihydroxyphenyl)-2-methyl-, L-
Methyldopa
L-a-Methyl-3,4-dihydroxyphenylalanine
(-)-Methyldopa
Elanpres
Density 1.4±0.1 g/cm3
Boiling Point 441.6±45.0 °C at 760 mmHg
Molecular Formula C10H13NO4
Molecular Weight 211.214
Flash Point 220.9±28.7 °C
Exact Mass 211.084457
PSA 103.78000
LogP 0.13
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.635
Storage condition −20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AY5940000
CHEMICAL NAME :
Alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-, DL-
CAS REGISTRY NUMBER :
555-29-3
LAST UPDATED :
199403
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C10-H13-N-O4
MOLECULAR WEIGHT :
211.24
WISWESSER LINE NOTATION :
QVXZ1&1R CQ DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5710 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
430 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5370 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1317 mg/kg
TOXIC EFFECTS :
Liver - hepatitis (hepatocellular necrosis), diffuse Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1318,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1760 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989
Hazard Codes Xi
Risk Phrases 36
Safety Phrases 26-36/37
WGK Germany 3