5699-41-2

5699-41-2 structure

Name: N-acetylputrescine
Chemical Name: N-(4-Aminobutyl)acetamide
CAS Number: 5699-41-2
Molecular Formula: C₆H₁₄N₂O
Molecular Weight: 130.18800
Catalog: Research Areas Cancer
Create Date: 2018-08-03 06:29:21
Modify Date: 2024-01-07 19:12:35
N-Acetylputrescine (NAP) is an endogenous metabolite widely present in animals and plants. N-Acetylputrescine can be used as a biomarker for lung squamous cell carcinoma (SCCL) and Parkinson's disease (PD) for disease diagnosis[1][2][3].

Name	N-(4-Aminobutyl)acetamide
Synonyms	N-acetylputrescinehydrochloride 1-acetylamino-4-aminobutane Acetylputrescine N1-acetylputrescine N-acetyl-1,4-butyl-diamine 4-acetylaminobutylamine monoacetylputrescine N-acetylputrescine Putrescine,N-acetyl

Description	N-Acetylputrescine (NAP) is an endogenous metabolite widely present in animals and plants. N-Acetylputrescine can be used as a biomarker for lung squamous cell carcinoma (SCCL) and Parkinson's disease (PD) for disease diagnosis[1][2][3].
Related Catalog	Research Areas >> Cancer Research Areas >> Neurological Disease
In Vitro	存在 [14C] 腐胺的情况下，N-Acetylputrescine 在人淋巴细胞中形成[4]。
References	[1]. Liu R, et al. Plasma N-acetylputrescine, cadaverine and 1,3-diaminopropane: potential biomarkers of lung cancer used to evaluate the efficacy of anticancer drugs. Oncotarget. 2017 Jul 17;8(51):88575-88585. [2]. Pfanzagl B, et al. N-acetylputrescine as a characteristic constituent of cyanelle peptidoglycan in glaucocystophyte algae. J Bacteriol. 1996 Dec;178(23):6994-7. [3]. Peng K W, et al. Identification and Validation of N-Acetylputrescine in Combination With Non-Canonical Clinical Features As a Parkinson’s Disease Biomarker Panel[J]. bioRxiv, 2021: 2021.07. 23.453542. [4]. Menashe M, et al. Formulation of N-acetylputrescine and N1-acetylspermidine in cultured human lymphocytes. Biochem J. 1980 Apr 15;188(1):263-7.

141-78-6

110-60-1

~55%

5699-41-2

Literature: Tang, Wei; Fang, Shiyue Tetrahedron Letters, 2008 , vol. 49, # 41 p. 6003 - 6006

110-60-1

122-79-2

~57%

5699-41-2

Literature: Pappas, Kyrie; Zhang, Xiang; Tang, Wei; Fang, Shiyue Tetrahedron Letters, 2009 , vol. 50, # 41 p. 5741 - 5743

830-03-5

110-60-1

~21%

5699-41-2

Literature: Pappas, Kyrie; Zhang, Xiang; Tang, Wei; Fang, Shiyue Tetrahedron Letters, 2009 , vol. 50, # 41 p. 5741 - 5743

141-78-6

110-60-1

~63%

5699-41-2

3073-57-2

13325-10-5

75-05-8

~33%

5699-41-2

Literature: Samant, Bhupesh S. European Journal of Medicinal Chemistry, 2008 , vol. 43, # 9 p. 1978 - 1982

101938-77-6

5699-41-2

Literature: Jackson Journal of Organic Chemistry, 1956 , vol. 21, p. 1374

110-60-1

75-36-5

5699-41-2

Literature: Suwal, Sujit; Senevirathne, Chamara; Garre, Satish; Pflum, Mary Kay H. Bioconjugate Chemistry, 2012 , vol. 23, # 12 p. 2386 - 2391

108-24-7

110-60-1

5699-41-2

Literature: Andruszkiewicz,R. et al. Polish Journal of Chemistry, 1978 , vol. 52, p. 2251 - 2254