N-acetylputrescine

Modify Date: 2025-08-25 16:57:16

N-acetylputrescine structure	Common Name	N-acetylputrescine
	CAS Number	5699-41-2	Molecular Weight	130.18800
	Density	0.948g/cm3	Boiling Point	301ºC at 760mmHg
	Molecular Formula	C₆H₁₄N₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	135.8ºC

Use of N-acetylputrescine

N-Acetylputrescine (NAP) is an endogenous metabolite widely present in animals and plants. N-Acetylputrescine can be used as a biomarker for lung squamous cell carcinoma (SCCL) and Parkinson's disease (PD) for disease diagnosis[1][2][3].

Name	N-(4-Aminobutyl)acetamide
Synonym	More Synonyms

Description	N-Acetylputrescine (NAP) is an endogenous metabolite widely present in animals and plants. N-Acetylputrescine can be used as a biomarker for lung squamous cell carcinoma (SCCL) and Parkinson's disease (PD) for disease diagnosis[1][2][3].
Related Catalog	Research Areas >> Cancer Research Areas >> Neurological Disease
In Vitro	存在 [14C] 腐胺的情况下，N-Acetylputrescine 在人淋巴细胞中形成[4]。
References	[1]. Liu R, et al. Plasma N-acetylputrescine, cadaverine and 1,3-diaminopropane: potential biomarkers of lung cancer used to evaluate the efficacy of anticancer drugs. Oncotarget. 2017 Jul 17;8(51):88575-88585. [2]. Pfanzagl B, et al. N-acetylputrescine as a characteristic constituent of cyanelle peptidoglycan in glaucocystophyte algae. J Bacteriol. 1996 Dec;178(23):6994-7. [3]. Peng K W, et al. Identification and Validation of N-Acetylputrescine in Combination With Non-Canonical Clinical Features As a Parkinson’s Disease Biomarker Panel[J]. bioRxiv, 2021: 2021.07. 23.453542. [4]. Menashe M, et al. Formulation of N-acetylputrescine and N1-acetylspermidine in cultured human lymphocytes. Biochem J. 1980 Apr 15;188(1):263-7.

Density	0.948g/cm3
Boiling Point	301ºC at 760mmHg
Molecular Formula	C₆H₁₄N₂O
Molecular Weight	130.18800
Flash Point	135.8ºC
Exact Mass	130.11100
PSA	58.61000
LogP	1.40200
Index of Refraction	1.48

N-acetylputrescine MSDS(Chinese)

ethyl acetate

CAS#:141-78-6

putrescine

CAS#:110-60-1

~55%

N-acetylputrescine

CAS#:5699-41-2

Literature: Tang, Wei; Fang, Shiyue Tetrahedron Letters, 2008 , vol. 49, # 41 p. 6003 - 6006

putrescine

CAS#:110-60-1

phenyl acetate

CAS#:122-79-2

~57%

N-acetylputrescine

CAS#:5699-41-2

Literature: Pappas, Kyrie; Zhang, Xiang; Tang, Wei; Fang, Shiyue Tetrahedron Letters, 2009 , vol. 50, # 41 p. 5741 - 5743

P-NITROPHENYLACETATE

CAS#:830-03-5

putrescine

CAS#:110-60-1

~21%

N-acetylputrescine

CAS#:5699-41-2

Literature: Pappas, Kyrie; Zhang, Xiang; Tang, Wei; Fang, Shiyue Tetrahedron Letters, 2009 , vol. 50, # 41 p. 5741 - 5743

ethyl acetate

CAS#:141-78-6

putrescine

CAS#:110-60-1

~63%

N-acetylputrescine

CAS#:5699-41-2

diacetylputrescine

CAS#:3073-57-2

Literature: Houen, Gunnar; Struve, Casper; Sondergaard, Roar; Friis, Tina; Anthoni, Uffe; Nielsen, Per H.; Christophersen, Carsten; Petersen, Bent O.; Duus, Jens . Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 11 p. 3783 - 3796

4-Amino-1-butanol

CAS#:13325-10-5

Acetonitrile

CAS#:75-05-8

~33%

N-acetylputrescine

CAS#:5699-41-2

Literature: Samant, Bhupesh S. European Journal of Medicinal Chemistry, 2008 , vol. 43, # 9 p. 1978 - 1982

N-(4-acetylamin...

CAS#:101938-77-6

N-acetylputrescine

CAS#:5699-41-2

Literature: Jackson Journal of Organic Chemistry, 1956 , vol. 21, p. 1374

putrescine

CAS#:110-60-1

Acetyl chloride

CAS#:75-36-5

N-acetylputrescine

CAS#:5699-41-2

Literature: Suwal, Sujit; Senevirathne, Chamara; Garre, Satish; Pflum, Mary Kay H. Bioconjugate Chemistry, 2012 , vol. 23, # 12 p. 2386 - 2391

Ethanoic anhydride

CAS#:108-24-7

putrescine

CAS#:110-60-1

N-acetylputrescine

CAS#:5699-41-2

Literature: Andruszkiewicz,R. et al. Polish Journal of Chemistry, 1978 , vol. 52, p. 2251 - 2254

Precursor 9
CAS#:141-78-6 ethyl acetate CAS#:110-60-1 putrescine CAS#:122-79-2 phenyl acetate CAS#:830-03-5 P-NITROPHENYLACETATE
CAS#:13325-10-5 4-Amino-1-butanol CAS#:75-05-8 Acetonitrile CAS#:101938-77-6 N-(4-acetylamin... CAS#:75-36-5 Acetyl chloride
CAS#:108-24-7 Ethanoic anhydride
DownStream 1
CAS#:34450-15-2 N8-Acetylspermi...

N-acetylputrescinehydrochloride

1-acetylamino-4-aminobutane

Acetylputrescine

N1-acetylputrescine

N-acetyl-1,4-butyl-diamine

4-acetylaminobutylamine

monoacetylputrescine

N-acetylputrescine

Putrescine,N-acetyl

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N-acetylputrescine

Use of N-acetylputrescine

Names

N-acetylputrescine Biological Activity

Chemical & Physical Properties

MSDS

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.