102013-72-9
102013-72-9 structure
- Name: m-PEG8-CH2COOH
- Chemical Name: 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
- CAS Number: 102013-72-9
- Molecular Formula: C19H38O11
- Molecular Weight: 442.49800
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2019-01-04 19:03:13
- Modify Date: 2024-01-06 17:20:40
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m-PEG8-CH2COOH is a PEG--based PROTAC linker can be used in the synthesis of PROTACs.
| Name | 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid |
|---|---|
| Synonyms |
3,6,9,12,15,18,21,24,27-nonaoxa-octacosanoic acid
3,6,9,12,15,18,21,24,27-Nonaoxa-octacosansaeure |
| Description | m-PEG8-CH2COOH is a PEG--based PROTAC linker can be used in the synthesis of PROTACs. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
[1]. Alexander Chucholowski, et al. Cyclodextrin conjugates. WO2010017328A2. |
| Density | 1.122 |
|---|---|
| Molecular Formula | C19H38O11 |
| Molecular Weight | 442.49800 |
| Exact Mass | 442.24100 |
| PSA | 120.37000 |
| Hazard Codes | Xi |
|---|
|
~%
102013-72-9 |
| Literature: CIBA Patent: US2769838 , 1954 ; |
| Precursor 1 | |
|---|---|
| DownStream 0 | |