Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Clopirac
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: Clopirac
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

42779-82-8

42779-82-8 structure

42779-82-8 structure

Name: Clopirac
Chemical Name: 2-[1-(4-chlorophenyl)-2,5-dimethylpyrrol-3-yl]acetic acid
CAS Number: 42779-82-8
Molecular Formula: C₁₄H₁₄ClNO₂
Molecular Weight: 263.71900
Catalog: Signaling Pathways Immunology/Inflammation PGE synthase
Create Date: 2018-06-19 12:19:06
Modify Date: 2024-01-10 10:07:23
Clopirac is a potent and orally active inhibitor of prostaglandin synthetase. Clopirac is an anti-inflammatory agent[1].

Name	2-[1-(4-chlorophenyl)-2,5-dimethylpyrrol-3-yl]acetic acid
Synonyms	1-p-Chlorphenyl-2,5-dimethyl-pyrrol-3-essigsaeure CP 172AP EINECS 255-938-5 CLOPIRAC

Description	Clopirac is a potent and orally active inhibitor of prostaglandin synthetase. Clopirac is an anti-inflammatory agent[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> PGE synthase
Target	prostaglandin synthetase[1]
References	[1]. Roba J, et al. Etude pharmacologique d'un nouvel anti-inflammatoire non stéroïdien, le clopirac [Pharmacological study of clopirac, a new anti-inflammatory agent (author's transl)]. J Belge Rhumatol Med Phys. 1975;30 Spec no:3-24.

Density	1.23g/cm3
Boiling Point	429.1ºC at 760mmHg
Molecular Formula	C₁₄H₁₄ClNO₂
Molecular Weight	263.71900
Flash Point	213.3ºC
Exact Mass	263.07100
PSA	42.23000
LogP	3.37460

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UX9277490

CHEMICAL NAME :: 1H-Pyrrole-3-acetic acid, 1-(4-chlorophenyl)-2,5-dimethyl-

CAS REGISTRY NUMBER :: 42779-82-8

BEILSTEIN REFERENCE NO. :: 0480479

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H14-Cl-N-O2

MOLECULAR WEIGHT :: 263.74

WISWESSER LINE NOTATION :: T5NJ AR DG& B1 C1VQ E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 780 mg/kg

TOXIC EFFECTS :: Behavioral - analgesia Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 11,173,1976

HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%