1020412-97-8

1020412-97-8 structure

Name: Tie-2 inhibitor 7
Chemical Name: 5-[4-[[(4-methylphenoxy)carbonyl-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]amino]methyl]phenyl]pyridine-3-carboxylic acid
CAS Number: 1020412-97-8
Molecular Formula: C₃₁H₃₅N₃O₅
Molecular Weight: 529.63
Catalog: Research Areas Cardiovascular Disease
Create Date: 2017-10-19 02:51:01
Modify Date: 2024-01-14 12:41:41
Tie2 kinase inhibitor 2 (compound 7) is a selective Tie2 kinase inhibitor with an IC50 value of 1 μM. Tie2 kinase inhibitor 2 inhibits endothelial cell tube formation, and can be used for Tie2-mediated angiogenic disorders research[1].

Name	5-[4-[[(4-methylphenoxy)carbonyl-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]amino]methyl]phenyl]pyridine-3-carboxylic acid
Synonyms	Tie-2 Inhibitor 7

Description	Tie2 kinase inhibitor 2 (compound 7) is a selective Tie2 kinase inhibitor with an IC50 value of 1 μM. Tie2 kinase inhibitor 2 inhibits endothelial cell tube formation, and can be used for Tie2-mediated angiogenic disorders research[1].
Related Catalog	Research Areas >> Cardiovascular Disease
Target	Tie2:1 μM (IC50) Tie2:1.3 μM (IC50)
References	[1]. Jinqi Liu, et al. Identification and characterization of small-molecule inhibitors of Tie2 kinase. FEBS Lett. 2008 Mar 5;582(5):785-91.