Tie-2 inhibitor 7

Modify Date: 2024-01-14 12:41:41

Tie-2 inhibitor 7 Structure
Tie-2 inhibitor 7 structure
Common Name Tie-2 inhibitor 7
CAS Number 1020412-97-8 Molecular Weight 529.63
Density N/A Boiling Point N/A
Molecular Formula C31H35N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tie-2 inhibitor 7


Tie2 kinase inhibitor 2 (compound 7) is a selective Tie2 kinase inhibitor with an IC50 value of 1 μM. Tie2 kinase inhibitor 2 inhibits endothelial cell tube formation, and can be used for Tie2-mediated angiogenic disorders research[1].

 Names

Name 5-[4-[[(4-methylphenoxy)carbonyl-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]amino]methyl]phenyl]pyridine-3-carboxylic acid
Synonym More Synonyms

 Tie-2 inhibitor 7 Biological Activity

Description Tie2 kinase inhibitor 2 (compound 7) is a selective Tie2 kinase inhibitor with an IC50 value of 1 μM. Tie2 kinase inhibitor 2 inhibits endothelial cell tube formation, and can be used for Tie2-mediated angiogenic disorders research[1].
Related Catalog
Target

Tie2:1 μM (IC50)

Tie2:1.3 μM (IC50)

References

[1]. Jinqi Liu, et al. Identification and characterization of small-molecule inhibitors of Tie2 kinase. FEBS Lett. 2008 Mar 5;582(5):785-91.  

 Chemical & Physical Properties

Molecular Formula C31H35N3O5
Molecular Weight 529.63
Exact Mass 523.21100
PSA 108.83000
LogP 6.02450

 Synonyms

Tie-2 Inhibitor 7