1160169-39-0

1160169-39-0 structure

Name: (Rac)-5-Keto Fluvastatin
Chemical Name: rac 5-Keto Fluvastatin
CAS Number: 1160169-39-0
Molecular Formula: C₂₄H₂₄FNO₄
Molecular Weight: 409.45000
Catalog: Signaling Pathways Metabolic Enzyme/Protease HMG-CoA Reductase (HMGCR)
Create Date: 2017-12-19 13:42:22
Modify Date: 2026-07-09 12:16:58
(Rac)-5-Keto Fluvastatin (3-Hydroxy-5-Keto Fluvastatin) is an impurity of Fluvastatin (XU 62320). Fluvastatin is a HMG-CoA reductase inhibitor with an IC50 of 8 nM[1].

Name	rac 5-Keto Fluvastatin
Synonyms	Fluvastatin Impurity 4 (Fluvastatin Impurity D) Fluvastatin Impurity D/3-hydroxy 5-keto Fluvastatin Fluvastatin IMP D 6-Htenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3-hydroxy-5-oxo-, (6E) Fluvastatin Sodium Impurity 4 Fluvastatin Sodium Impurity D 5 Oxo Fluvastatin (6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3-hydroxy-5-oxoht-6-enoic Acid Fluvastatin impurity D (6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3-hydroxy-5-oxoht-6-enoic Acid (5-Keto (E)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3-hydroxy-5-oxohept-6-enoic acid

Description	(Rac)-5-Keto Fluvastatin (3-Hydroxy-5-Keto Fluvastatin) is an impurity of Fluvastatin (XU 62320). Fluvastatin is a HMG-CoA reductase inhibitor with an IC50 of 8 nM[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR)
References	[1]. Araújo FA, Rocha MA, Capettini LS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24. [Epub ahead of print]