125391-75-5

125391-75-5 structure

Name: 2-Amino-3’-deoxy-3’-fluoroadenosine
Chemical Name: (2R,3S,4S,5R)-2-(2,6-diaminopurin-9-yl)-4-fluoro-5-(hydroxymethyl)oxolan-3-ol
CAS Number: 125391-75-5
Molecular Formula: C₁₀H₁₃FN₆O₃
Molecular Weight: 284.25
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-10-31 00:55:36
Modify Date: 2024-01-06 15:00:18
2-Amino-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	(2R,3S,4S,5R)-2-(2,6-diaminopurin-9-yl)-4-fluoro-5-(hydroxymethyl)oxolan-3-ol
Synonyms	Adenosine,2-amino-3'-deoxy-3'-fluoro-(9CI) 3'F-2-NH2-3'dA 3'-Fluoro-3'-deoxy-2-aminoadenosine Adenosine,2-amino-3'-deoxy-3'-fluoro

Description	2-Amino-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.