2-Amino-3’-deoxy-3’-fluoroadenosine

Modify Date: 2024-01-06 15:00:18

2-Amino-3’-deoxy-3’-fluoroadenosine Structure
2-Amino-3’-deoxy-3’-fluoroadenosine structure
Common Name 2-Amino-3’-deoxy-3’-fluoroadenosine
CAS Number 125391-75-5 Molecular Weight 284.25
Density 2.17g/cm3 Boiling Point 748.9ºC at 760 mmHg
Molecular Formula C10H13FN6O3 Melting Point N/A
MSDS N/A Flash Point 406.7ºC

 Use of 2-Amino-3’-deoxy-3’-fluoroadenosine


2-Amino-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name (2R,3S,4S,5R)-2-(2,6-diaminopurin-9-yl)-4-fluoro-5-(hydroxymethyl)oxolan-3-ol
Synonym More Synonyms

 2-Amino-3’-deoxy-3’-fluoroadenosine Biological Activity

Description 2-Amino-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.17g/cm3
Boiling Point 748.9ºC at 760 mmHg
Molecular Formula C10H13FN6O3
Molecular Weight 284.25
Flash Point 406.7ºC
Exact Mass 284.10300
PSA 146.06000
Vapour Pressure 1.47E-23mmHg at 25°C
Index of Refraction 1.903

 Synonyms

Adenosine,2-amino-3'-deoxy-3'-fluoro-(9CI)
3'F-2-NH2-3'dA
3'-Fluoro-3'-deoxy-2-aminoadenosine
Adenosine,2-amino-3'-deoxy-3'-fluoro