Name | 3,4,5-trimethoxycinnamic acid |
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Synonyms |
3,4,5-Trimethoxycinnamic
o-methylsinapicacid 3,4,5-Trimethoxy cinnamic acid (2E)-3-(3,4,5-Trimethoxyphenyl)acrylic acid 2-Propenoic acid, 3-(3,4,5-trimethoxyphenyl)-, (2E)- 3,4,5-Trimethoxycinnamic acid 2-propenoic acid, 3-(3,4,5-trimethoxyphenyl)- TRIMETHOXYCINNAMICACID 3,4,5-trimethoxy-cinnamicaci 5-TriMethoxycinnaMic acid 3-(3,4,5-trimethoxyphenyl)prop-2-enoic acid EINECS 201-999-8 3,4,5-Trimethoxyzimtsure RARECHEM BK HC T328 MFCD00004388 |
Description | 3,4,5-Trimethoxycinnamic acid is a phenylpropanoid isolated from the roots of Polygala tenuifoliaWILLD, with anti-stress effect, prolonging the sleeping time in animals[1][2]. 3,4,5-Trimethoxycinnamic acid increases expression of GAD65 and γ-subunit of GABAA receptor, but shows no effect on the amounts of α-, β-subunits[2]. |
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Related Catalog | |
Target |
γ-subunit of GABAA receptor[2] |
In Vitro | 3,4,5-Trimethoxycinnamic acid (10 μg/ml) increases expression of GAD65 and γ-subunit of GABAA receptor, but shows no effect on the amounts of α-, β-subunits[2]. |
In Vivo | 3,4,5-Trimethoxycinnamic acid (25-100 mg/kg, i.p.) exhibits sedative effect, and prolongs the sleeping time in rats[1]. 3,4,5-Trimethoxycinnamic acid (10 mg/kg, p.o.) significantly decreases locomotor activity in mice[2]. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 396.4±37.0 °C at 760 mmHg |
Melting Point | 125-127 °C(lit.) |
Molecular Formula | C12H14O5 |
Molecular Weight | 238.237 |
Flash Point | 151.5±20.0 °C |
Exact Mass | 238.084122 |
PSA | 64.99000 |
LogP | 2.00 |
Vapour Pressure | 0.0±1.0 mmHg at 25°C |
Index of Refraction | 1.560 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi: Irritant; |
Safety Phrases | S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 2 |
RTECS | GE0722000 |
HS Code | 2916399090 |
Precursor 0 | |
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DownStream 6 | |
HS Code | 2916399090 |
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Summary | 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |