Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,5,8,11,14-pentaoxahexadecan-16-oic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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16024-66-1

16024-66-1 structure

16024-66-1 structure

Name: m-PEG4-CH2COOH
Chemical Name: 2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]acetic acid
CAS Number: 16024-66-1
Molecular Formula: C₁₁H₂₂O₇
Molecular Weight: 266.28800
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-09-01 13:00:49
Modify Date: 2024-01-09 19:04:52
m-PEG4-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

Name	2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]acetic acid
Synonyms	3,6,9,12,15-pentoxahexadecanoic acid MPEG4-acetic acid (2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethoxy)acetic acid 3,6,9,12,15-Pentaoxahexadecansaeure EINECS 240-163-7 3,6,9,12,15-Pentaoxahexadecanoicacid 2,5,8,11,14-Pentaoxahexadecan-16-oic acid

Description	m-PEG4-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. TaoDeng, et al. Monodisperse oligoethylene glycols modified Propofol prodrugs. Bioorganic & Medicinal Chemistry Letters.

Density	1.125g/cm3
Boiling Point	379.6ºC at 760 mmHg
Molecular Formula	C₁₁H₂₂O₇
Molecular Weight	266.28800
Flash Point	137.1ºC
Exact Mass	266.13700
PSA	83.45000
Vapour Pressure	8.24E-07mmHg at 25°C
Index of Refraction	1.447

Hazard Codes	Xi
HS Code	2918990090

23778-52-1 structure

23778-52-1

~50%

16024-66-1 structure

16024-66-1

Literature: Heimann, Ulrich; Voegtle, Fritz Liebigs Annalen der Chemie, 1980 , # 6 p. 858 - 862

23783-42-8 structure

23783-42-8

79-08-3 structure

79-08-3

~%

16024-66-1 structure

16024-66-1

Literature: Tuchscherer; Schaarschmidt; Schulze; Hietschold; Lang Dalton Transactions, 2012 , vol. 41, # 9 p. 2738 - 2746

52995-76-3 structure

52995-76-3

~%

16024-66-1 structure

16024-66-1

Literature: Heimann, Ulrich; Voegtle, Fritz Liebigs Annalen der Chemie, 1980 , # 6 p. 858 - 862

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%