147837-52-3

147837-52-3 structure

Name: N-Acetyl-Val-Ala-Asp-al
Chemical Name: (3S)-3-[[(2S)-2-[[(2S)-2-acetamido-3-methylbutanoyl]amino]propanoyl]amino]-4-oxobutanoic acid
CAS Number: 147837-52-3
Molecular Formula: C₁₄H₂₃N₃O₆
Molecular Weight: 329.349
Catalog: Biochemical Peptide
Create Date: 2018-12-24 13:35:14
Modify Date: 2024-01-04 07:53:34
Ac-VAD-CHO (Ac-Val-Ala-Asp-CHO) is a pan-caspase inhibitor. Ac-VAD-CHO inhibits dissipation of MMP and cytochrome c release in hypoxia-exposed cells[1].

Name	(3S)-3-[[(2S)-2-[[(2S)-2-acetamido-3-methylbutanoyl]amino]propanoyl]amino]-4-oxobutanoic acid
Synonyms	Ac-VAD-CHO N-acetyl-L-valyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-alaninamide N-Acetyl-Val-Ala-Asp-al L-Alaninamide,N-acetyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]-(9CI) L-Alaninamide, N-acetyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]- N-Acetyl-L-valyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-alaninamide Ac-Val-Ala-Asp-CHO L-alaninamide,N-acetyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl] Caspase Inhibitor II L-Alaninamide,N-acetyl-L-valyl-N-(2-carboxy-1-formylethyl)-,(S)

Description	Ac-VAD-CHO (Ac-Val-Ala-Asp-CHO) is a pan-caspase inhibitor. Ac-VAD-CHO inhibits dissipation of MMP and cytochrome c release in hypoxia-exposed cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Caspase
References	[1]. Jee-Youn Kim, et al. ROS-dependent caspase-9 activation in hypoxic cell death. FEBS Lett. 2003 Aug 14;549(1-3):94-8.

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