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253449-04-6

253449-04-6 structure
253449-04-6 structure
  • Name: Wiskostatin
  • Chemical Name: 1-(3,6-dibromocarbazol-9-yl)-3-(dimethylamino)propan-2-ol
  • CAS Number: 253449-04-6
  • Molecular Formula: C17H18Br2N2O
  • Molecular Weight: 426.146
  • Catalog: Signaling Pathways Cytoskeleton Arp2/3 Complex
  • Create Date: 2018-12-31 20:42:48
  • Modify Date: 2026-06-30 10:24:14
  • Wiskostatin is a potent and selective inhibitor of neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin polymerization. Wiskostatin causes a rapid, profound, and irreversible decrease in cellular ATP levels[1].

Name 1-(3,6-dibromocarbazol-9-yl)-3-(dimethylamino)propan-2-ol
Synonyms WISKOSTATIN
9H-Cbazole-9-ethanol, 3,6-dibromo-α-[(dimethylamino)methyl]
1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(dimethylamino)-2-propanol
9H-Cbazole-9-ethanol, 3,6-dibroMo-alpha-[(diMethylaMino)Methyl]
1-(3,6-dibromo-9H-carbazol-9-yl)-3-(dimethylamino)propan-2-ol
Wiskostatin, N-WASP inhibitor
(S)-WISKOSTATIN
3,6-Dibromo-9-[3-(dimethylamino)-2-hydroxyprop-1-yl]-9H-cbazole, 3-(3,6-Dibromo-9H-cbazol-9-yl)-N,N-dimethyl-2-hydroxypropylamine
1-(3,6-Dibromo-9H-cbazol-9-yl)-3-(dimethylamino)propan-2-ol
Wiskostatin - - Calbiochem
Wiskostatin,neuronal,ATP,irreversible,p2/3 Complex,inhibit,N-WASP,selective,Inhibitor,Actin-related protein 2/3 complex,actin polymerization
1-(3,6-Dibromo-carbazol-9-yl)-3-dimethylamino-propan-2-ol
1-(3,6-dibromocarbazol-9-yl)-3-dimethylaminopropan-2-ol
3,6-Dibromo-α-[(dimethylamino)methyl]-9H-cabazole-9-ethanol
3,6-Dibromo-α-[(dimethylamino)methyl]-9H-cbazole-9-ethanol
Wiskostatin, 10 mM in DMSO
3,6-Dibromo-alpha-[(dimethylamino)methyl]-9H-cbazol-9-ethanol
1-(3,6-dibromocbazol-9-yl)-3-(dimethylamino)propan-2-ol
Description Wiskostatin is a potent and selective inhibitor of neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin polymerization. Wiskostatin causes a rapid, profound, and irreversible decrease in cellular ATP levels[1].
Related Catalog
References

[1]. Guerriero CJ, et al. N-WASP inhibitor wiskostatin nonselectively perturbs membrane transport by decreasing cellular ATP levels. Am J Physiol Cell Physiol. 2007;292(4):C1562-C1566.

Density 1.6±0.1 g/cm3
Boiling Point 320.2±22.0 °C at 760 mmHg
Melting Point 153-155ºC
Molecular Formula C17H18Br2N2O
Molecular Weight 426.146
Flash Point 147.4±22.3 °C
Exact Mass 423.978577
PSA 28.40000
LogP 5.65
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.657
Storage condition 2-8°C
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H413
Precautionary Statements P301 + P310
Hazard Codes Xi: Irritant;C: Corrosive;
RIDADR UN3259
HS Code 2933990090
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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