Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-(BENZO[D]OXAZOL-2-YL)ANILINE
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Purity: 98.0%
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20934-81-0

20934-81-0 structure

20934-81-0 structure

Name: 4-(BENZO[D]OXAZOL-2-YL)ANILINE
Chemical Name: 4-(1,3-benzoxazol-2-yl)aniline
CAS Number: 20934-81-0
Molecular Formula: C₁₃H₁₀N₂O
Molecular Weight: 210.23100
Catalog: Research Areas Cancer
Create Date: 2018-07-25 13:08:35
Modify Date: 2024-01-08 12:34:25
4-(Benzo[d]oxazol-2-yl)aniline is a potent antitumor agent. 4-(Benzo[d]oxazol-2-yl)aniline has inhibitory activity against mammary carcinoma cell lines[1].

Name	4-(1,3-benzoxazol-2-yl)aniline
Synonyms	4-Benzoxazol-2-ylphenylamine 4-Benzooxazol-2-yl-phenylamine

Description	4-(Benzo[d]oxazol-2-yl)aniline is a potent antitumor agent. 4-(Benzo[d]oxazol-2-yl)aniline has inhibitory activity against mammary carcinoma cell lines[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	4-(Benzo[d]oxazol-2-yl)aniline (compound 5b) (0-100 μM; 7 days for MCF-7 and 10 days for MDA 468) has inhibitory activity against MCF-7 and MDA 468 mammary carcinoma cell lines[1]. Cell Proliferation Assay[1] Cell Line: MCF-7 and MDA 468 Concentration: 0-100 μM Incubation Time: 7 days for MCF-7 and 10 days for MDA 468 Result: Exhibited inhibitory activity against MCF-7 (IC50>0.01-0.1 μM) and MDA 468 (IC50>0.1-1 μM).
References	[1]. Shi DF, et al. Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo. J Med Chem. 1996 Aug 16;39(17):3375-84.

Density	1.257g/cm3
Boiling Point	361.4ºC at 760mmHg
Molecular Formula	C₁₃H₁₀N₂O
Molecular Weight	210.23100
Flash Point	172.4ºC
Exact Mass	210.07900
PSA	52.05000
LogP	3.65820
Vapour Pressure	2.08E-05mmHg at 25°C
Index of Refraction	1.682

Hazard Codes	Xi
HS Code	2934999090

Precursor 10
150-13-0 95-55-6 2835-68-9 583-53-9
273-53-0 106-40-1 455-14-1 109-86-4
840-58-4 556-18-3
DownStream 4
100476-63-9 100476-59-3 100476-58-2 16707-41-8

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%