Shanghai Nianxing Industrial Co., Ltd
China
Product Name: sAJM589
Price:
Purity: 99.0%
Stocking Period: 10 Day
Contact: Huang

ShangHai DC Chemicals Co.,Ltd
China
Product Name: sAJM-589
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

DC Chemicals Limited
China
Product Name: sAJM-589
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2089-82-9

2089-82-9 structure

2089-82-9 structure

Name: sAJM-589
Chemical Name: 6H-benzo[a]phenazin-5-ol
CAS Number: 2089-82-9
Molecular Formula: C₁₆H₁₀N₂O
Molecular Weight: 246.26300
Catalog: Signaling Pathways Apoptosis c-Myc
Create Date: 2016-08-13 16:58:41
Modify Date: 2024-02-03 12:07:31
sAJM-589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM[1].

Name	6H-benzo[a]phenazin-5-ol
Synonyms	3-Hydroxy-1,2-benzophenazin

Description	sAJM-589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> c-Myc
Target	IC50: 1.8 μM (Myc)[1]
In Vitro	sAJM-589 potently disrupts the Myc-Max heterodimer in a dose dependent manner with an IC50of 1.8 μM[1]. sAJM589 suppresses cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage independent growth of Raji cells[1].
References	[1]. Choi SH, et al. Targeted Disruption of Myc-Max Oncoprotein Complex by a Small Molecule. ACS Chem Biol. 2017 Nov 17;12(11):2715-2719.

Molecular Formula	C₁₆H₁₀N₂O
Molecular Weight	246.26300
Exact Mass	246.07900
PSA	46.01000
LogP	3.64180

HS Code	2933990090

Precursor 0
DownStream 4
225-61-6 61316-12-9 61316-17-4 61316-66-3

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%