109792-60-1
109792-60-1 structure
- Name: Boc-DADdec
- Chemical Name: 1-boc-1,12-diaminododecane
- CAS Number: 109792-60-1
- Molecular Formula: C17H36N2O2
- Molecular Weight: 300.48000
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-10-06 21:01:18
- Modify Date: 2024-01-09 18:33:56
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Boc-NH-C12-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 1-boc-1,12-diaminododecane |
|---|---|
| Synonyms |
Boc-DADdec
TERT-BUTYL 12-AMINODODECYLCARBAMATE N-Boc-1,12-dodecanediamine N-t-Butyloxycarbonyl-1,12-diaminododecane N-tert-butoxycarbonyl-1,12-diaminododecane 1,12-Diaminododecane,N-BOC protected tert-butyl 2,13-diaMinotridecanoate mono-tert-butoxycarbonyl-1,12-diaminododecane |
| Description | Boc-NH-C12-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 0.924g/cm3 |
|---|---|
| Boiling Point | 409.2ºC at 760mmHg |
| Molecular Formula | C17H36N2O2 |
| Molecular Weight | 300.48000 |
| Flash Point | 201.3ºC |
| Exact Mass | 300.27800 |
| PSA | 64.35000 |
| LogP | 5.46200 |
| Vapour Pressure | 6.61E-07mmHg at 25°C |
| Index of Refraction | 1.463 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi: Irritant; |
| RIDADR | NONH for all modes of transport |
| HS Code | 2924199090 |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |